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Efforts to address the poor prognosis associated with esophageal adenocarcinoma (EAC) have been hampered by a lack of biomarkers to identify early disease and therapeutic targets. Despite extensive efforts to understand the somatic mutations associated with EAC over the past decade, a gap remains in...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD042792 | Pride
Genomic instability due to defective DNA damage response or arising from mitotic chromosomal imbalance can lead to sequestration of DNA in aberrant extranuclear structures called micronuclei (MN). Although MN are a hallmark of genomic instability associated diseases and ageing, the catalogue of gen...
ORGANISM(S): Homo sapiens (Human) 
2023-11-17 | PXD030499 | Pride
In this project we aimed to explore the effect of Dscc1 gene loss on the proteome. Embyros from wildtype and aged matched Dssc1 null embryos were profiled.
ORGANISM(S): Mus musculus (Mouse) 
2023-11-17 | PXD034902 | Pride
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