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TranscriptomicsTranscription profiling of normal and tumorigenic Rattus norvegicus cell lines grown under normal and arginine deprivation conditions
Goals of the Study:; 1. Assess the scope of arginine-responsive hepatic gene expression using in vitro rat models. 2. Compare normal and tumorigenic cells; 3. Identify potentially novel genes and pathways that may be subject to amino acid (arginine) regulation; Background: We previously reported t...
ORGANISM(S): Rattus norvegicus 
2007-10-08 | E-GEOD-2275 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli arginine regulon using wild type and argR- strains grown on medium with and without arginine
Analysis of the response to arginine of the Escherichia coli K-12 transcriptome by microarray hybridization and real-time quantitative PCR provides a first coherent quantitative picture of the ArgR-mediated repression of arginine biosynthesis and uptake genes. Transcriptional repression was shown to...
ORGANISM(S): Escherichia coli 
2007-10-24 | E-GEOD-4724 | biostudies-arrayexpress
ProteomicsMBEC4 cells with low-Arginine conditions
Amino acid transporters are expressed in the brain capillary endothelial cells, which form the blood-brain barrier, and their expression levels change during the neonatal period. This study aimed to investigate the molecular mechanisms regulating the amino acid transporter levels in mouse brain capi...
ORGANISM(S): Mus Musculus (mouse) 
2025-04-11 | PXD054477 | JPOST Repository
TranscriptomicsArgR1 and AhrC Mediate Arginine-Dependent Regulation of Arginine Acquisition- and Virulence Genes in the Human Pathogen Streptococcus pneumoniae
This SuperSeries is composed of the following subset Series: GSE33033: ahrC mutant compared to D39 wild-type in Streptococcus pneumoniae in CDM + 10 mM arginine GSE33034: argR1 mutant compared to D39 wild-type in Streptococcus pneumoniae in CDM + 10 mM arginine GSE33035: argR1-ahrC mutant compared t...
ORGANISM(S): Streptococcus pneumoniae D39 
2011-11-02 | E-GEOD-33043 | biostudies-arrayexpress
TranscriptomicsStreptococcus pneumoniae D39 wild-type grown in CDM+10 mM arginine compared to D39 wild type grown in CDM + 0.05 mM arginine
Comparison of Streptococcus pneumoniae D39 wild-type grown in CDM+10 mM arginine compared to D39 wild type grown in CDM + 0.05 mM arginine to define the genome-wide transcriptional response to arginine. Details described in Kloosterman TG and Kuipers OP. ArgR1 and AhrC Mediate Arginine-Dependent Re...
ORGANISM(S): Streptococcus pneumoniae D39 
2011-11-02 | E-GEOD-33036 | biostudies-arrayexpress
MetabolomicsMitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance
Not available
ORGANISM(S): Homo sapiens 
ST001730 | MetabolomicsWorkbench
TranscriptomicsExpression data from murine colon tissue after exposure to 4% DSS for 6 days DSS followed by 4 days of water or 1% L-arginine
L-Arginine (L-Arg) is the substrate for both inducible nitric oxide synthase and arginase, which are upregulated in human IBD and in mouse colitis models. We have found that L-Arg supplementation enhances wound restitution in vitro, and improves the clinical parameters of weight loss, survival, and ...
ORGANISM(S): Mus musculus 
2012-06-26 | E-GEOD-34874 | biostudies-arrayexpress
MetabolomicsL-Citrulline and L-arginine regulate the reproductive performance of young and adult cows through distinct metabolic pathways and the shared pyrimidine metabolic pathway respectively

(Background)To investigate the impact of L-arginine (L-Arg) and L-citrulline (L-Cit) on cow reproductive performance.(Methods) 90 healthy, age-matched Simmental cows were randomly assigned to three groups: control, L-Arg, and L-Cit, with 30 cows per group. Estrus synchronization was performed, an...

2025-07-05 | MTBLS12682 | MetaboLights
MetabolomicsMitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance (part-III)
Not available
ORGANISM(S): Homo sapiens 
ST001732 | MetabolomicsWorkbench
MetabolomicsMitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance (part-II)
Not available
ORGANISM(S): Homo sapiens 
ST001731 | MetabolomicsWorkbench
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