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ProteomicsEffects of chronic social stress on mitochondrial and mitochondrial-associated membrane protein networks in the mouse brain
Stressors challenge metabolic processes to adapt to ever-changing environmental conditions and herein, the brain is exceptionally amenable to change. Simultaneously, the high cerebral energy demands may render the brain particularly vulnerable to the metabolic consequences of psychological stress. M...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-13 | PXD015983 | Pride
Mitochondrial-associated membrane Brain Mouse Chronic stress 
ProteomicsGDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton
Charcot-Marie-Tooth (CMT) disease 4A is an autosomal-recessive polyneuropathy caused by mutations of ganglioside-induced differentiation-associated protein 1 (GDAP1), a putative glutathione transferase, which affects mitochondrial shape and alters cellular Ca2+ homeostasis. Here, we identify the und...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD028460 | Pride
Β-oxidation Lc-ms Gdap1 
Proteomics1GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton
Charcot-Marie-Tooth (CMT) disease 4A is an autosomal-recessive polyneuropathy caused by mutations of ganglioside-induced differentiation-associated protein 1 (GDAP1), a putative glutathione transferase, which affects mitochondrial shape and alters cellular Ca2+homeostasis. Here, w...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD024555 | Pride
Mouse Gdap1 Pulldown Sp3 Lc-udmse Primary cortical neurons 
OtherCell physiology of the biotechnological relevant bacterium Bacillus pumilus-an omics-based approach.
Data from ProteomeXchange, PXD ID: PXD000780. Experiment: O2_U1_gmr_sh_11_1, file: 100223_O2_U1_gmr_sh_11_1_4.mzml. Published as part of J Biotechnol. 2014 Dec 20;192 Pt A:204-14 . From the Abstract: {{i}} Members of the species Bacillus pumilus get more and more in focus of the biotechnological in...
ORGANISM(S): Crap, Bacillus_pumilus_safr_032 
GPM32310018327 | GPMDB
Resource Reanalysis 
TranscriptomicsEpigenetic Maintenance of Stemness and Malignancy in Peripheral Neuroectodermal Tumors by EZH2
Chromatin modifications are increasingly recognized as a key mechanism in cancer. The histone methyl-transferase Enhancer of Zeste, Drosophila, Homolog 2 (EZH2) is the enzymatic subunit of the polycomb PRC2 complex and methylates histone H3K27, thereby, mediating gene silencing. Down-regulation of E...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-15890 | biostudies-arrayexpress
UnknownMethotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial.
Not available
S-EPMC4486345 | biostudies-literature
GenomicsAffymetrix_miRNA4.0
Primary renal cell carcinoma (RCC) by Affymetrix GeneChip miRNA 4.0
EGAD00010001564 | EGA
GenomicsPDX_HTA2.0_Guergen2022
GeneChip HTA 2.0 data of primary renal cell carcinoma (RCC) and RCC metastases related to Guergen et al, Front Oncol 12:2022 889789. Microarrays were normalized individually using the SCAN method from the R package SCAN.UPC (version 2.34.0). Probe sets were summarized on the Entrez GeneID level usin...
EGAD00010002392 | EGA
GenomicsAffymetrix_HTA2.0
Primary renal cell carcinoma (RCC) and RCC metastases by Affymetrix GeneChip HTA 2.0
EGAD00010001589 | EGA
GenomicsRCC_HTA2.0_Reustle2020
GeneChip HTA 2.0 data of primary renal cell carcinoma (RCC) related to Reustle et al, Genome Med 12:2020 32. Preprocessing of microarray data was performed using Robust Multi-array Average (RMA).
EGAD00010002323 | EGA
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