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HUVEC were exposed to 1 mM sodium nitroprusside (SNP) for 2, 4, 8 and 24 hours and compared to untreated control cells.
ORGANISM(S): Homo sapiens 
HUVEC were exposed to 0.1, 1 and 10 mM sodium nitroprusside (SNP) for 4 hours and compared to untreated control cells.
ORGANISM(S): Homo sapiens 
Human clinical trials in type 1 diabetes (T1D) patients are underway using mesenchymal stem cells (MSC) without prior validation in a mouse model for the disease. In response to this void, we characterized bone marrow-derived murine MSC for their ability to modulate immune responses in the context ...
ORGANISM(S): Mus musculus 
Genomic enhancers are important regulators of gene expression, but their identification is a challenge and methods depend on indirect measures of activity. We developed a method termed STARR-seq to directly and quantitatively assess enhancer activity for millions of candidates from arbitrary sources...
ORGANISM(S): Homo sapiens 
Helicobacter pylori enhances the risk for ulcer disease and gastric cancer, yet only a minority of H. pylori-colonized individuals develop disease. We examined the ability of two H. pylori isolates to induce differential host responses in vivo or in vitro, and then used an H. pylori whole genome mic...
ORGANISM(S): Helicobacter pylori 
Cells in culture undergo replicative senescence and unequivocally stop proliferation after a limited number of cell divisions. In this study, we have expanded mesenchymal stem cells (MSC) from human adipose tissue and analyzed genetic and epigenetic sequels. The subpopulation of highly proliferative...
ORGANISM(S): Homo sapiens 
We examined the changes in gene expression in Arabidopsis thaliana grown under arsenate stress. The transcriptional profiling reveals antioxidant activity and repression of the phosphate starvation response. Keywords: dual label, stress response This experiment included a comparison of three biolog...
ORGANISM(S): Arabidopsis thaliana 
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