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TranscriptomicsAberrantly expressed genes in HaCaT keratinocytes chronically exposed to arsenic trioxide
The purpose of this study is to search for aberrant genes in HaCaT keratinocytes after chronic exposure to arsenic trioxide. The objective of the investigation was to discover the mechanism of arsenic carcinogenicity in human epidermal keratinocytes. We hypothesize that a combined strategy of DNA mi...
ORGANISM(S): Homo sapiens 
2012-04-11 | E-GEOD-37192 | biostudies-arrayexpress
ProteomicsFremont et al 2023 - Arsenic stress triggers active exudation of arsenic-phytochelatin complexes from Lupinus albus roots
Arsenic stress triggers active exudation of arsenic-phytochelatin complexes from Lupinus albus roots
ORGANISM(S): Lupinus Albus (ncbitaxon:3870) 
2023-10-10 | MSV000093078 | MassIVE
TranscriptomicsGenomic responses to arsenic in Synechocystis
Arsenic is an ubiquitous contaminant and a toxic metalloid which presents two main redox states in nature: arsenite [AsIII] and arsenate [AsV]. Arsenic resistance in Synechocystis sp. strain PCC 6803 is mediated by the arsBHC operon and two additional arsenate reductases encoded by the arsI1 and ars...
ORGANISM(S): Synechocystis sp. PCC 6803 
2014-05-13 | E-GEOD-51383 | biostudies-arrayexpress
Transcriptomicstemporal transcriptomic response during arsenic stress in Rhizobium NT-26
The objective of this study is to identify genes involved in arsenic stress and more particularly to see whether the presence of arsenic can highlight a link between mobility and oxidation
ORGANISM(S): Rhizobium NT-26 
2011-01-01 | E-MEXP-3021 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human U266, MM.1s, KMS11, 8226/S multiple myeloma cell lines treated with arsenic
We used microarrays to examine changes in gene expression in multiple myeloma cell lines following treatment with arsenic trioxide and darinaparsin Experiment Overall Design: Four multiple myeloma cell lines (U266, MM.1s, KMS11, 8226/S) were treated with either arsenic trioxide (ATO) for 6, 24, or 4...
ORGANISM(S): Homo sapiens 
2009-02-01 | E-GEOD-14519 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Puga- tBHQ and arsenic treated GCLM-WT and KO mice
Evaluate the protective effect of prior tBHQ treatment from arsenic damage at two dosage levels of arsenic (2 and 20 uM), and compare to the effect of tBHQ or arsenic treatment given alone.
ORGANISM(S): Mus musculus 
2005-12-08 | E-MEXP-371 | biostudies-arrayexpress
TranscriptomicsComparative transcriptome analysis of transporters, phytohormone and lipid metabolism pathways in response to arsenic stress in rice (Oryza Sativa L.)
Arsenic (As) is a carcinogenic metalloid that is a contaminant widely polluting rice paddy soils around the world. In order to gain better insight into molecular mechanism of rice exposed to As(III) stress, we used next-generation sequencing technology to acquire global transcriptome alteration and ...
ORGANISM(S): Oryza sativa Japonica Group 
2013-01-09 | E-GEOD-36696 | biostudies-arrayexpress
TranscriptomicsArsenic-induced Changes in L2 Cells
Arsenic is a carcinogen that is known to induce cell transformation and tumor formation. Although studies have been performed to examine the modulation of signaling molecules caused by arsenic exposure, the molecular mechanisms by which arsenic causes cancer are still unclear. We hypothesized that ...
ORGANISM(S): Rattus norvegicus 
2011-12-23 | E-GEOD-9790 | biostudies-arrayexpress
TranscriptomicsWhole genome expression profile of lung epithelial cells following chronic arsenic exposure
This study chronically exposed human lung epithelial BEAS-2B cells to low-dose arsenic trioxide in vitro to elucidate cancer promoting gene signaling networks (GSNs) associated with As-transformed (B-As) cells. Following a six month exposure, exposed cells were assessed for enhanced cell proliferat...
ORGANISM(S): Homo sapiens 
2012-09-26 | E-GEOD-33520 | biostudies-arrayexpress
ProteomicsProteomic response of Staphylococcus sp. NIOSBK35 to varying arsenic (III) concentrations
Protein expression in Staphylococcus sp. NIOSBK35 isolated from marine environment (mangrove sediments) to different concentrations of arsenic (III)
ORGANISM(S): Staphylococcus cohnii 
2019-12-02 | PXD013569 | Pride
Arsenic (iii) Lc-ms qtof Marine-derived Peptide mass fingerprinting 
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