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TranscriptomicsEffect of Artemisinin on Aspergillus fumigatus gene expression program
We examined the antifungal activity of artemisinin against Aspergillus fumigatus (A. fumigatus), a pathogenic filamentous fungus responsible for allergic and invasive aspergillosis in humans and analyzed transcript profiles of the fungus on exposure to Artemisinin. A. fumigatus spores were cultured ...
ORGANISM(S): Aspergillus fumigatus 
2011-05-11 | E-GEOD-21297 | biostudies-arrayexpress
MetabolomicsMulti-omics based identification of specific biochemical changes associated with PfKelch13-mutant artemisinin resistant Plasmodium
Not available
ORGANISM(S): Plasmodium falciparum 
ST000546 | MetabolomicsWorkbench
MetabolomicsK13 mutations driving artemisinin resistance rewrite Plasmodium falciparum’s programmed intra-erythrocytic development and transform mitochondrial physiology
Not available
ORGANISM(S): Plasmodium falciparum 
ST001279 | MetabolomicsWorkbench
UnknownRed and Blue Light Promote the Accumulation of Artemisinin in Artemisia Annua L.
Not available
S-EPMC6100300 | biostudies-literature
ProteomicsHeme-activated Promiscuous Targeting of Artemisinin in Plasmodium falciparum
Plasmodium falciparum, the most pathogenic human malaria parasite, infects millions of human beings and causes a serious public health threat. Currently, the most potent anti-malarial drugs are artemisinin and its derivatives1,2. Artemisinin is a sesquiterpene lactone with an endoperoxide bridge3. T...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2015-12-17 | PXD002611 | Pride
Mechanism of action Target Artemisinin Chemical proteomics 
TranscriptomicsStructural polymorphism in the promoter of pfmrp2 confers tolerance to mefloquine and chloroquine in Plasmodium falciparum [CGH]
Drug resistance in Plasmodium falciparum remains a challenge for the malaria eradication programs around the world. With the emergence of artemisinin resistance, the efficacy of the partner drugs in the artemisinin combination therapies (ACT) that include quinoline based drugs is becoming critical. ...
ORGANISM(S): Plasmodium falciparum 
2013-02-07 | E-GEOD-44128 | biostudies-arrayexpress
ProteomicsMetabolisme of artemisinin-resistant falciparum malaria parasites: are apicoplast and mitochondrion pathways key targets?
In the context of artemisinin resistance, the objective of the project was to evaluate the role of apicoplast and mitochondrion pathways during the parasite quiescent state induced by dihydroartemisinin (DHA) treatment. We analysed the proteome of artemisinin-resistant parasites in two conditions: a...
ORGANISM(S): Plasmodium falciparum 
2025-05-06 | PXD048354 | Pride
Artemisinin resistance  metabolism  apicoplast  mitochondrion  quiescence 
TranscriptomicsStructural polymorphism in the promoter of pfmrp2 confers tolerance to mefloquine and chloroquine in Plasmodium falciparum [expression]
Drug resistance in Plasmodium falciparum remains a challenge for the malaria eradication programs around the world. With the emergence of artemisinin resistance, the efficacy of the partner drugs in the artemisinin combination therapies (ACT) that include quinoline based drugs is becoming critical. ...
ORGANISM(S): Plasmodium falciparum 
2013-02-07 | E-GEOD-44127 | biostudies-arrayexpress
UnknownCombined chemical transformation and biological transformation of artemisinin: A facile approach to diverse artemisinin derivatives.
Not available
S-EPMC9902651 | biostudies-literature
TranscriptomicsApplication of a 9k-cDNA microarray for identification of albendazole and artemisinin targeting genes in Echinococcus granulosus larval protoscoleces
A cDNA microarray composed of 9065 uniEST probes was constructed and applied to detect the gene expression profile of protoscoleces of E. granulosus treated with albendazole and artemisinin in vitro, respectively. Compared with the untreated parasite, 7 genes were up-regulated and 38 genes were down...
ORGANISM(S): Echinococcus granulosus 
2014-06-03 | E-GEOD-58136 | biostudies-arrayexpress
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