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GenomicsA master cistromic circuit governing hepatic fibrogenesis [ChIP-seq]
Liver fibrosis is a reversible wound-healing response to liver injury and hepatic stellate cells (HSCs) are central cellular players that mediate hepatic fibrogenesis. However, the molecular mechanisms that govern this process remain unclear. Here, we reveal a novel cistromic circuit in HSCs compris...
ORGANISM(S): Homo sapiens 
2013-04-29 | E-GEOD-38103 | biostudies-arrayexpress
ProteomicsBone marrow-derived mast cells +- IL-33 48h
Mast cells are tissue resident granulocytes which are most abundant at the interface between tissues and the external environment, such as around blood vessels, in the skin or mucosal surfaces in the lungs and gut. Pathologically they are involved in allergic reactions and anaphylaxis, however they ...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD033759 | Pride
Granulocyte Mouse Lc-ms Mast cell Il-33 
TranscriptomicsA Master Cistromic Circuit Governing Hepatic Fibrogenesis
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Rattus norvegicus 
2013-04-29 | E-GEOD-41580 | biostudies-arrayexpress
UnknownCost-Effectiveness of Pembrolizumab as First-Line Treatment in Patients with Persistent, Recurrent, or Metastatic Cervical Cancer in the United States.
Not available
S-EPMC11880493 | biostudies-literature
Unknown"I can guess the month … but beyond that, I can't tell" an exploratory qualitative study of health care provider perspectives on gestational age estimation in Rajasthan, India.
Not available
S-EPMC7488485 | biostudies-literature
UnknownNRF2 is required for neonatal mouse beta cell growth by maintaining redox balance and promoting mitochondrial biogenesis and function.
Not available
S-EPMC11521447 | biostudies-literature
TranscriptomicsEpigenetic profiling at mouse imprinted gene clusters
Epigenetic profiling of DNA methylation, histone H3 lysine 4 trimethylation and histone H3 lysine 9 trimethylation at imprinted gene clusters in the mouse. Imprinted control regions were identified by comparing DNA and histone methylation patterns between sperm, heart and cerebellum.
ORGANISM(S): Mus musculus 
2010-05-18 | E-GEOD-16588 | biostudies-arrayexpress
ProteomicsBeta-cell Galphas signaling is critical for physiological and pharmacological enhancement of insulin secretion
Islet lysates were adjusted to 5 percent SDS in TEAB, pH 8.5, reduced and alkylated and digested with modified trypsin (Worthington) using an S-trap mini device (Protifi). Peptides were labeled with TMT16 reagents (lot ZH350094). Phosphopeptide enrichment used GL Sciences p10 TiO tips. LC-MS/MS used...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-05-13 | MSV000097882 | MassIVE
UnknownSingle-centre, single-blinded, randomised, parallel group, feasibility study protocol investigating if mandibular advancement device treatment for obstructive sleep apnoea can reduce nocturnal gastro-oesophageal reflux (MAD-Reflux trial).
Not available
S-EPMC10450077 | biostudies-literature
TranscriptomicsTranscription profiling of mouse Dnmt3L+/- sires compared to offspring of Dnmt3L+/+ sires to investigate the effect of paternal haploinsufficiency for Dnmt3L
There is increasing evidence that epigenetic information can be inherited across generations in mammals, despite extensive reprogramming both in the gametes and the early developing embryo. One corollary to this is that disruption of the establishment of epigenetic state in the gametes of a parent, ...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7384 | biostudies-arrayexpress
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