Sort   by:  
 Page size 
ProteomicsProteomics of Asrij perturbed Drosophila lymph glands as a resource for identification of new regulators of hematopoiesis
Hematological disorders result in perturbed homeostasis of the blood system. However, a comprehensive understanding of how physiological and genetic mechanisms regulate blood cell precursor maintenance and differentiation is lacking. Owing to simplicity and ease of genetic analysis, the Drosophila m...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2019-05-15 | PXD010753 | Pride
Lymph gland Asrij Differential regulation Escrt Drosophila hematopoiesis Proteome 
GenomicsOrganelle dysfunction upon asrij depletion causes aging-like changes in mouse hematopoietic stem cells
Organelle dysfunction upon asrij depletion causes aging-like changes in mouse hematopoietic stem cells
PRJNA793873 | ENA
GenomicsAsrij/OCIAD1 expression delineates functionally distinct hematopoietic stem cells in the bone marrow
Asrij/OCIAD1 expression delineates functionally distinct hematopoietic stem cells in the bone marrow
PRJNA1294836 | ENA
TranscriptomicsOrganelle dysfunction upon asrij depletion causes aging-like changes in mouse hematopoietic stem cells
Asrij deletion in mice causes loss of HSC quiescence, myeloid skewing, reduced p53 and increased DNA damage, features attributed to aged hematopoietic stem cells (HSCs). To identify the pathways and processes driving the observed HSC aging-like phenotypes upon asrij depletion and to compare the asri...
ORGANISM(S): Mus musculus 
2022-01-06 | GSE192948 | GEO
GenomicsAsrij/OCIAD1 depletion reduces inflammatory microglial activation and ameliorates Aβ pathology in an Alzheimer's disease mouse model
Asrij/OCIAD1 depletion reduces inflammatory microglial activation and ameliorates Aβ pathology in an Alzheimer's disease mouse model
PRJNA1137854 | ENA
TranscriptomicsAsrij/OCIAD1 expression delineates functionally distinct hematopoietic stem cells in the bone marrow
Hematopoietic stem cells (HSCs) within the bone marrow (BM) display significant molecular and functional heterogeneity. Deciphering intrinsic factors that govern HSC diversity is key to enriching specific HSC subtypes for predictable and clinically relevant differentiation outcomes. Here, we show th...
ORGANISM(S): Mus musculus 
2026-01-01 | GSE303327 | GEO
TranscriptomicsAsrij/OCIAD1 depletion reduces inflammatory microglial activation and ameliorates Aβ pathology in an Alzheimer's disease mouse model
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the accumulation of amyloid-beta (Ab) plaques and neurofibrillary tangles, neuroinflammation, and glial activation. Asrij/OCIAD1 (Ovarian Carcinoma Immunoreactive Antigen Domain containing protein 1) is an AD-associated factor...
ORGANISM(S): Mus musculus 
2024-07-20 | GSE272625 | GEO
UnknownAsrij/OCIAD1 contributes to age-associated microglial activation and neuroinflammation in mice.
Not available
S-EPMC12549667 | biostudies-literature
UnknownAsrij maintains the stem cell niche and controls differentiation during Drosophila lymph gland hematopoiesis.
Not available
S-EPMC3215734 | biostudies-literature
UnknownOrganelle dysfunction upon asrij depletion causes aging-like changes in mouse hematopoietic stem cells.
Not available
S-EPMC9009118 | biostudies-literature
Sort   by:  
 Page size