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MetabolomicsConserved leaf–root metabolomic network asymmetry underpins divergent drought strategies
Plants orchestrate tissue-specific metabolic responses to osmotic stress, a major determinant of drought tolerance and crop productivity. Yet how leaf and root responses are coordinated to confer tolerance remains poorly understood. Here we show that drought tolerance in wheat is associated with a r...
2026-07-22 | MTBLS15125 | MetaboLights
ProteomicsEpigenetic contributions to hemisphere asymmetry in healthy brain, aging, and Parkinson’s disease
Hemispheric asymmetry in neuronal processes is a fundamental feature of the human brain and drives symptom lateralization in Parkinson's disease (PD), but its molecular determinants are unknown. Here, we determine epigenetic changes and genes involved in hemispheric asymmetry in the healthy and PD b...
ORGANISM(S): Homo sapiens (Human) 
2020-03-26 | PXD015239 | Pride
Enhancer Neurons Epigenetics Parkinson’s disease Hemisphere asymmetry Aging 
GenomicsStrand asymmetry in MPRA Signal
Strand asymmetry in MPRA Signal
PRJNA659269 | ENA
TranscriptomicsMasseter muscle gene expression in human malocclusion subjects with and without posterior facial asymmetry
Non-syndromic facial asymmetry is commonly found in dentofacial deformity populations with skeletal malocclusions. Asymmetry of this type may result from imbalanced growth and function of both the jaw and associated muscles. Among the multiple genes that interact to affect the craniofacial muscu...
ORGANISM(S): Homo sapiens 
2014-05-20 | E-GEOD-57775 | biostudies-arrayexpress
TranscriptomicsSmall-RNA asymmetry is directly driven by mammalian Argonautes
Asymmetric selection of single-stranded guide RNAs from double-stranded RNA (dsRNA) precursors is crucial for RNA silencing-mediated gene regulation. However, the precise mechanisms for small RNA asymmetry remain unclear, especially since asymmetric selection can still occur under depletion of putat...
ORGANISM(S): Mus musculus 
2015-06-15 | E-GEOD-66022 | biostudies-arrayexpress
TranscriptomicsTranscriptome partitioning in mouse fertilization.
RNA transcripts are distributed non-uniformly in the oocytes of many animals, such that newly-divided embryo cells (blastomeres) inherit distinct transcriptomes following fertilization. In animals such as the frog, Xenopus laevis, programmed transcript regionalization directs early embryonic axis fo...
ORGANISM(S): Mus musculus 
2011-04-21 | E-GEOD-27396 | biostudies-arrayexpress
OtherStrand asymmetry in MPRA Signal
We analyzed data from sequencing-based massively parallel reporter assays (MPRAs) retaining the strand orientation of the alignments. These analyses showed pervasive asymmetry in reporter signal from test element strand orientation. Present in elements derived from all regions of the human genome, w...
ORGANISM(S): Homo sapiens 
2020-12-04 | GSE156857 | GEO
GenomicsSmall-RNA asymmetry is directly driven by mammalian Argonautes
Asymmetric selection of single-stranded guide RNAs from double-stranded RNA (dsRNA) precursors is crucial for RNA silencing-mediated gene regulation. However, the precise mechanisms for small RNA asymmetry remain unclear, especially since asymmetric selection can still occur under depletion of putat...
ORGANISM(S): Mus musculus 
2015-06-15 | GSE66022 | GEO
TranscriptomicsMasseter muscle gene expression in human malocclusion subjects with and without posterior facial asymmetry
Non-syndromic facial asymmetry is commonly found in dentofacial deformity populations with skeletal malocclusions. Asymmetry of this type may result from imbalanced growth and function of both the jaw and associated muscles. Among the multiple genes that interact to affect the craniofacial musculosk...
ORGANISM(S): Homo sapiens 
2014-05-20 | GSE57775 | GEO
GenomicsAsymmetry and redundancy of STAT5 paralogs across CD8+ T cell differentiation states
Asymmetry and redundancy of STAT5 paralogs across CD8+ T cell differentiation states
PRJNA1425165 | ENA
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