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ProteomicsMeta-Analysis and DIA-MS-based Proteomic Investigation of COPD Patients and Asymptomatic Smokers in the Indian population
Chronic obstructive pulmonary disease (COPD) is India's second largest cause of death and is largely caused by smoking. Asymptomatic smokers develop COPD due to genetic, environmental, and molecular variables, making early screening crucial. Data-independent acquisition mass spectrometry (DIA-MS) pr...
ORGANISM(S): Homo sapiens (Human) 
2024-11-13 | PXD055242 | Pride
Smokers Healthy subjects Proteomics Dia Indian population : copd Asymptomatic smokers 
ProteomicsMeta-Analysis and DIA-MS-based Proteomic Investigation of COPD Patients and Asymptomatic Smokers in the Indian population
Chronic obstructive pulmonary disease (COPD) is the second leading cause of death in India, primarily attributed to smoking. Asymptomatic smokers can develop COPD due to a combination of genetic, environmental, and molecular factors, highlighting the importance of early detection. Data-independent a...
ORGANISM(S): Homo Sapiens 
2024-11-13 | PXD055103 | panorama
TranscriptomicsUpregulation of Expression of Matrix Metalloproteinases in Alveolar Macrophages of HIV1+ Smokers with Early Emphysema
HIV1+ smokers develop emphysema at an earlier age and with a higher incidence than HIV1- smokers. Based on the knowledge that human alveolar macrophages (AM) are capable of producing proteases that degrade extracellular matrix components, we hypothesized that upregulation of AM matrix metalloprotein...
ORGANISM(S): Homo sapiens 
2016-03-24 | E-GEOD-10038 | biostudies-arrayexpress
ProteomicsAlterations in the sputum proteome and transcriptome in smokers and early-stage COPD patients
Chronic obstructive pulmonary disease (COPD) is one of the most prevalent lung diseases, and involves persistent airflow limitation and incorporates both emphysema and chronic bronchitis. Cigarette smoking has been identified as the main risk factor for disease development and progression. In a basi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-21 | MSV000080275 | MassIVE
MetabolomicsChronic Obstructive Pulmonary Disease (COPD) Biomarker Identification Study: Serum Lipidomics
The overall clinical study used a parallel-group, case-controlled study design in order to identify a biomarker or panel of biomarkers for the differentiation of subjects with mild to moderate COPD (GOLD stage I and II), asymptomatic current smokers, former smokers and never-smokers and to compare p...
2017-02-20 | MTBLS358 | MetaboLights
TranscriptomicsComparative genomic hybridization of normal karyotype lung tumors from heavy smokers using Affymetrix SNP arrays
Whole genome analysis on normal karyotype lung tumors from heavy smokers.
Our study regarded a population of 5203 heavy smokers volunteers, enrolled in a screening program set up at the European Institute of Oncology. Each volunteer yearly undergoes low dose CT-scan. At the end of the second ...
ORGANISM(S): Homo sapiens 
2009-11-20 | E-MEXP-2450 | biostudies-arrayexpress
UnknownAssociation of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers.
Not available
S-EPMC1140754 | biostudies-literature
UnknownClinical Significance of Symptoms in Smokers with Preserved Pulmonary Function.
Not available
S-EPMC4968204 | biostudies-literature
UnknownAGER expression and alternative splicing in bronchial biopsies of smokers and never smokers.
Not available
S-EPMC6456980 | biostudies-literature
UnknownAssociation between smoking status and subclinical coronary atherosclerosis in asymptomatic Korean individuals.
Not available
S-EPMC11576522 | biostudies-literature
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