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ProteomicsProteomic phenotyping of stimulated Müller cells uncovers profound pro-inflammatory signaling and antigen-presenting capacity
Müller cells are the main macroglial cells of the retina exerting a wealth of functions to maintain retinal homoeostasis. Upon pathological changes in the retina, they become gliotic with both protective and detrimental consequences. Accumulating data also provide evidence for a pivotal role of Müll...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2022-02-16 | PXD028390 | Pride
Pro-inflammatory Complement system Cytokines. retina Immune response Müller cells Atypical antigen-presenting cell Diabetic retinopathy 
TranscriptomicsChIP-chip from KG-1 cells with HIV Tat
HIV-1 Tat can modulate the expression of both HIV and cellular genes. In antigen-presenting cells Tat induces the expression of a subset of interferon-stimulated genes (ISGs) in the absence of interferons (IFNs). We investigated the genome-wide Tat association with cellular promoters in immature den...
ORGANISM(S): Homo sapiens 
2013-05-31 | E-GEOD-42191 | biostudies-arrayexpress
TranscriptomicsMuscle - atypical diabetes protein expression
Skeletal muscle biopsies from atypical diabetics at presentation and remission. Protein expression determined with antibody arrays
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-634 | biostudies-arrayexpress
UnknownMyD88/CD40 Genetic Adjuvant Function in Cutaneous Atypical Antigen-Presenting Cells Contributes to DNA Vaccine Immunogenicity.
Not available
S-EPMC5065236 | biostudies-literature
GenomicsMHC II-expressing bone marrow megakaryocytes are noncanonical antigen presenting cells and activate CD4+ T cells ex vivo
MHC II-expressing bone marrow megakaryocytes are noncanonical antigen presenting cells and activate CD4+ T cells ex vivo
PRJNA1454938 | ENA
UnknownAtypical TRAV1-2- T cell receptor recognition of the antigen-presenting molecule MR1.
Not available
S-EPMC7573270 | biostudies-literature
TranscriptomicsMHC II-expressing bone marrow megakaryocytes are noncanonical antigen presenting cells and activate CD4+ T cells ex vivo
While professional antigen-presenting cells drive adaptive immunity, atypical cell types can fulfill this role in the bone marrow. Megakaryocytes (MKs) are canonically recognized for platelet production, but recent studies indicate functional heterogeneity and immune potential. We found that ~20% of...
ORGANISM(S): Mus musculus 
2026-09-24 | GSE328415 | GEO
TranscriptomicsTranscription profiling of CD8+ T cells from BM3.3 transgenic mice during responses to TCR ligands of different avidity
To identify the molecular bases for divergence in differentiation programs of naïve CD8 T cells, we monitored gene expression profile of CD8+ T cells from BM3.3 transgenic mice during responses to TCR ligands of different avidity (full response with antigen presenting cells from C57BL/6 mice , parti...
ORGANISM(S): Mus musculus 
2004-07-07 | E-MEXP-16 | biostudies-arrayexpress
UnknownProteomic Phenotyping of Stimulated Muller Cells Uncovers Profound Pro-Inflammatory Signaling and Antigen-Presenting Capacity.
Not available
S-EPMC8585775 | biostudies-literature
UnknownAtypical sideways recognition of CD1a by autoreactive γδ T cell receptors.
Not available
S-EPMC9256601 | biostudies-literature
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