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UnknownAssociation of genetically predicted testosterone with thromboembolism, heart failure, and myocardial infarction: mendelian randomisation study in UK Biobank.
Not available
S-EPMC6402044 | biostudies-literature
TranscriptomicsGene expression analysis of OVCAR-3 and CDK2 resistant sublines
Cyclin E1 (CCNE1) is amplified in various tumor types including high-grade serous ovarian cancer where it is associated with poor clinical outcome. We have demonstrate that suppression of the Cyclin E1 partner kinase, CDK2, induces apoptosis in a CCNE1 amplicon-dependent manner. Little is known of m...
ORGANISM(S): Homo sapiens 
2013-09-01 | E-GEOD-48919 | biostudies-arrayexpress
UnknownDo iron homeostasis biomarkers mediate the associations of liability to type 2 diabetes and glycemic traits in liver steatosis and cirrhosis: a two-step Mendelian randomization study.
Not available
S-EPMC11210020 | biostudies-literature
TranscriptomicsCopy number analysis of OVCAR-3 and CDK2 resistant sublines
Cyclin E1 (CCNE1) is amplified in various tumor types including high-grade serous ovarian cancer where it is associated with poor clinical outcome. We have demonstrate that suppression of the Cyclin E1 partner kinase, CDK2, induces apoptosis in a CCNE1 amplicon-dependent manner. Little is known of m...
ORGANISM(S): Homo sapiens 
2013-09-01 | E-GEOD-48920 | biostudies-arrayexpress
TranscriptomicsGene expression and copy number analysis of OVCAR-3 and CDK2 resistant sublines
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-09-01 | E-GEOD-48921 | biostudies-arrayexpress
GenomicsDAC for Dave Lab, Duke University
Data Access Committee EGAC00001000538
EGAC00001000538 | EGA
Genomicsena-DATASET-DAVELAB-22-03-2017-21:30:50:663-38 - samples
Whole exome sequencing of hepatosplenic T cell lymphoma (HSTL) tumors, paired normals, and cell lines, including (1) 68 exome capture, paired-end Illumina Hiseq sequencing, BAM files from HSTL tumor samples, (2) 20 exome capture, paired-end Illumina Hiseq sequencing, BAM files from HSTL paired norma...
EGAD00001003246 | EGA
Genomicsena-DATASET-DAVELAB-01-09-2017-13:58:58:766-116 - samples
Exome sequencing data for 1001 DLBCL patients and RNA sequencing data for 775 DLBCL patients
EGAD00001003600 | EGA
GenomicsGenetic and Functional Drivers of Diffuse Large B Cell Lymphoma
Diffuse large B cell lymphoma (DLBCL) is the most common hematologic malignancy and is characterized by a striking degree of heterogeneity. We enrolled a total of 1001 DLBCL patients and comprehensively defined the landscape of genetic mutations, copy number alterations and expression through whole-...
EGAS00001002606 | EGA
GenomicsGenetic Basis of Hepatosplenic T Cell Lymphoma (HSTL)
Hepatosplenic T cell lymphoma (HSTL) is a rare and lethal lymphoma; the genetic drivers of this disease are unknown.  Through whole exome sequencing of 68 HSTLs, we define recurrently mutated driver genes and copy number alterations in the disease. Chromatin modifying genes including SETD2, INO80 an...
EGAS00001002182 | EGA
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