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TranscriptomicsTranscriptomic assessment of resistance to effects of an aryl hydrocarbon receptor (AHR) agonist in embryos of Atlantic killifish (Fundulus heteroclitus) from a marine Superfund site
This study presents statistical analyses of gene expression in 5, 10 and 15 day post-fertilization (dpf) embryos of the teleost Fundulus heteroclitus treated with control vehicle (DMSO) or a potent non-ortho-PCB (PCB-126; 3,3’,4,4’,5-pentachlorobiphenyl). The embryos were from two populations: a cl...
ORGANISM(S): Fundulus heteroclitus 
2011-06-06 | E-GEOD-25245 | biostudies-arrayexpress
UnknownHighly specific σ<sub>2</sub>R/TMEM97 ligand FEM-1689 alleviates neuropathic pain and inhibits the integrated stress response.
Not available
S-EPMC10756276 | biostudies-literature
UnknownHighly specific σ2R/TMEM97 ligand alleviates neuropathic pain and inhibits the integrated stress response.
Not available
S-EPMC10120691 | biostudies-literature
TranscriptomicsGene expression profiling of laparoscopic donor nephrectomy samples compared to healthy control kidneys
We compared gene expression profiles from six donor kidneys prior to surgical manipulation to six kidneys removed after laparoscopic donor nephrectomy (LDN) and several hours of CO2 pneumoperitoneum. Biopsies were obtained from renal cortex and hybridized to Affymetrix HG-U133A GeneChips. For cont...
ORGANISM(S): Homo sapiens 
2005-09-14 | E-GEOD-3297 | biostudies-arrayexpress
ProteomicsTriple SILAC exosomal quantitative proteomic analysis
Exosomes are 30-100 nm sized membrane vesicles released by cells into extracellular space and mediate the intercellular communication via transfer of proteins and RNAs. To better understand the function of these microvesicles in lung carcinogenesis, we employed a Triple SILAC quantitative proteomic ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-02 | MSV000079882 | MassIVE
UnknownMolecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology phase II basket trial.
Not available
S-EPMC4356709 | biostudies-literature
ProteomicsTriple SILAC glycoproteomic analysis of NSCLC cell lines
Protein glycosylation plays a fundamental role in a multitude of biological processes, and the associated aberrant expression of glycoproteins in cancer has made them attractive targets as biomarkers and therapeutic targets. In this study, we examined differentially expressed glycoproteins in cell l...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-10 | MSV000079569 | MassIVE
MetabolomicsGNPS - MITOMICS: defining mitochondrial protein functions through deep multi-omic profiling
Mitochondria are epicenters of eukaryotic metabolism and bioenergetics. Pioneering efforts in recent decades have established the core protein componentry of these organelles and have linked their dysfunction to over 150 distinct disorders. However, hundreds of mitochondrial proteins still lack clea...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-11 | MSV000086685 | GNPS
ProteomicsDevelopment of a Robust Score and False Discovery Rate for Metabolite Identification
We used machine learning (ML) to improve metabolite identification confidence in GC-MS data. This project was funded by PNNL's M/Q initiative. All data was collected on an Agilent GC 7890A coupled with a single quadrupole MSD 5975C. Metabolites were derivatized prior to analysis.
ORGANISM(S): Trichoderma Reesei (ncbitaxon:51453) Aspergillus (ncbitaxon:5052) Homo Sapiens (ncbitaxon:9606) Aspergillus Nidulans (ncbitaxon:162425) 
2022-07-20 | MSV000089933 | MassIVE
TranscriptomicsGene expression profiles in lymph nodes from ferrets infected with A/California/07/2009
Pandemic H1N1 influenza A Human infection leads to symptoms ranging from mild to severe with lower respiratory complications observed in a small but significant number of infected individuals. Microarray analysis of the lymph nodes from ferrets infected with A/California/07/2009 shows intense gene u...
ORGANISM(S): Mustela putorius furo 
2013-01-28 | E-GEOD-36019 | biostudies-arrayexpress
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