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UnknownDisparities by Sexual Orientation in Frequent Engagement in Cancer-Related Risk Behaviors: A 12-Year Follow-Up.
Not available
S-EPMC4785035 | biostudies-literature
UnknownPerceived Cognitive Deficits in a Sample of Persons Living With Multiple Sclerosis.
Not available
S-EPMC5657431 | biostudies-literature
TranscriptomicsUpregulated stromal EGFR and vascular remodeling in human NSCLC murine models (xenografts) of VEGF inhibitor resistance
The mechanisms by which tumors develop resistance to angiogenesis inhibitors, and the relative contributions of tumor cells and stroma to resistance, are not completely understood. We developed three human lung adenocarcinoma murine models of resistance to the VEGF inhibitor bevacizumab and, using s...
ORGANISM(S): Homo sapiens 
2011-04-22 | E-GEOD-26644 | biostudies-arrayexpress
TranscriptomicsPdx-1 activates islet M-NM-1- and M-NM-2-cell proliferation via a TRPC3/6- and ERK 1/2-regulated mechanism
The homeodomain transcription factor, Pdx-1, has important roles in pancreatic development and M-NM-2-cell function and survival. In the present study, we demonstrate that adenovirus-mediated overexpression of Pdx-1 in rat or human islets also stimulates cell replication. Moreover, co-overexpression...
ORGANISM(S): Rattus norvegicus 
2013-09-01 | E-GEOD-49786 | biostudies-arrayexpress
TranscriptomicsTransition of embryonic stem cells from ground state pluripotency
Mouse embryonic stem cells were maintained in minimal and chemically-defined culture conditions supporting naive pluripotency. Inhibitors of the Gsk3 (CHIR99021) and Mek/Erk (PD0325901) pathways were withdrawn, cultures maintained for 24 hours, and subsequently sorted by flow cytometry based on fluo...
ORGANISM(S): Mus musculus 
2017-02-22 | E-MTAB-5304 | biostudies-arrayexpress
TranscriptomicsWhole blood gene expression in female Balb/c mice following 2-week Pb exposure and subsequent 2-week recovery period
Background: Current evidence indicates that even low-level lead (Pb) exposure can have detrimental effects, especially in children. We tested the hypothesis that Pb exposure alters gene expression patterns in peripheral blood cells and that these changes reflect dose-specific alterations in the acti...
ORGANISM(S): Mus musculus 
2011-03-30 | E-GEOD-28261 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Bos taurus surgical model of the jejunum infected with Bovine rotavirus (BRV) and bovine coronavirus (BCV)
Bovine rotavirus (BRV) and bovine coronavirus (BCV) infect intestinal villous epithelium in young cattle. A surgical model was adapted for neonatal calves in which a region of the jejunum was isolated from the digestive tract but lymph drainage, enervation and blood flow were maintained. Replicate s...
ORGANISM(S): Bos taurus 
2005-01-01 | E-FPMI-3 | biostudies-arrayexpress
TranscriptomicsKc167 ORC2 Localization
modENCODE_submission_674 This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We will precisely identify sequence elements that direct DNA replication by using chromatin immunoprecipitation of known r...
ORGANISM(S): Drosophila melanogaster 
2010-05-15 | E-GEOD-17282 | biostudies-arrayexpress
TranscriptomicsKc167 MCM Localization
modENCODE_submission_675 This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We will precisely identify sequence elements that direct DNA replication by using chromatin immunoprecipitation of known r...
ORGANISM(S): Drosophila melanogaster 
2010-05-15 | E-GEOD-17283 | biostudies-arrayexpress
TranscriptomicsGenomics-based molecular epidemiology of human clinical and feedlot cattle C. jejuni isolates in Alberta, Canada
Oligonucleotide DNA microarrays were used as a platform to compare C. jejuni isolates from feedlot cattle and human clinical cases from Alberta. Comparative genomic hybridization (CGH) analysis was performed on 87 isolates (46 bovine, 41 human) obtained within the same geographical regions and time ...
ORGANISM(S): Campylobacter jejuni 
2010-05-18 | E-GEOD-13228 | biostudies-arrayexpress
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