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MetabolomicsCyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs (Murine kidney and plasma UPLC-MS/MS assay)

BACKGROUND: Large-scale, placebo-controlled trials established that nonsteroidal anti-inflammatory drugs confer a cardiovascular hazard: this has been attributed to depression of cardioprotective products of cyclooxygenase (COX)-2, especially prostacyclin. An alternative mechanis...

2019-08-22 | MTBLS680 | MetaboLights
UnknownHow hydrogel inclusions modulate the local mechanical response in early and fully formed post-infarcted myocardium.
Not available
S-EPMC7484038 | biostudies-literature
UnknownEvolution of the Human Cytokine Response from Acute Illness to Disease Resolution in SARS-Cov-2 Infection-Implications for Therapeutic Monitoring and Therapeutic Targets.
Not available
S-EPMC8051826 | biostudies-literature
UnknownCOVID-MATCH65-A prospectively derived clinical decision rule for severe acute respiratory syndrome coronavirus 2.
Not available
S-EPMC7725390 | biostudies-literature
UnknownAre NKT cells a useful predictor of COVID-19 severity?
Not available
S-EPMC8768020 | biostudies-literature
UnknownInternational Network of Antibiotic Allergy Nations (iNAAN): Protocol for a type 2 hybrid effectiveness-implementation multicentre prospective cohort and target trial emulation study evaluating penicillin allergy delabeling via direct oral challenge.
Not available
S-EPMC12412947 | biostudies-literature
TranscriptomicsGene Expression in Inflammatory Diseases
We hypothesized that patients with sarcoidosis have characteristic mRNA profiles. Microarray analysis of gene expression was done on peripheral blood. Comparing peripheral blood from patients with sarcoidosis to controls, 872 transcripts were upregulated and 1039 were downregulated at >1.5-fold chan...
ORGANISM(S): Homo sapiens 
2009-11-04 | E-GEOD-18781 | biostudies-arrayexpress
UnknownExploring cytokine outputs for <i>ex vivo</i> diagnostics in drug reaction with eosinophilia and systemic symptoms (DRESS).
Not available
S-EPMC11665396 | biostudies-literature
GenomicsNHLBI GO-ESP Family Studies: Pulmonary Arterial Hypertension

The NHLBI "Grand Opportunity" Exome Sequencing Project (GO-ESP), a signature project of the NHLBI Recovery Act investment, was designed to identify genetic variants in coding regions (exons) of the human genome (the "exome") that are associated with heart, lung and blood diseases. These and relat...

phs000354.v1.p1 | EGA
MetabolomicsCyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs (Murine and human plasma quantitative L-arginine and methylarginines UPLC-MS/MS assay)

BACKGROUND: Large-scale, placebo-controlled trials established that nonsteroidal anti-inflammatory drugs confer a cardiovascular hazard: this has been attributed to depression of cardioprotective products of cyclooxygenase (COX)-2, especially prostacyclin. An alternative mechanis...

2019-08-22 | MTBLS685 | MetaboLights
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