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TranscriptomicsFunctional and evolutionary significance of human microRNA seed region mutations
This SuperSeries is composed of the SubSeries listed below. Data for miR-429, miR-205, miR-200b, and miR-141 were each compared independently to the same negative control data contained in the raw .CEL files nc-miR-1-1.CEL, nc-miR-1-2.CEL and nc-miR-1-3.CEL. For each miRNA, the negative control da...
ORGANISM(S): Homo sapiens 
2015-01-30 | E-GEOD-56973 | biostudies-arrayexpress
UnknownWhat Is the Effect of Vitamin C on Finger Stiffness After Distal Radius Fracture? A Double-blind, Placebo-controlled Randomized Trial.
Not available
S-EPMC6999927 | biostudies-literature
TranscriptomicsMethamphetamine administration causes differential alterations in gene expression and dynamic patterns of histone acetylation/hypoacetylation in the rat nucleus accumbens
Methamphetamine (METH) addiction is associated with a plethora of neuropsychiatric symptoms. In rodents, administration of the drug is accompanied by complex changes in gene expression in the dorsal striatum. Very little is known about the effects of the drug on gene expression and epigenetic modifi...
ORGANISM(S): Rattus norvegicus 
2011-07-31 | E-GEOD-31081 | biostudies-arrayexpress
TranscriptomicsThe Central Role of c-Myc during Malignant Conversion in Human Hepatocarcinogenesis
Hepatocarcinogenesis is a multi-stage process in which precursor lesions progress into early hepatocellular carcinomas (eHCC) by sequential accumulation of multiple genetic and epigenetic alterations. To decode the molecular events during early stages of liver carcinogenesis, we performed gene expre...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-12443 | biostudies-arrayexpress
TranscriptomicsGenes altered by miR-634 in three cancer cell lines
To identify genes affected by miR-634 overexpression, we transfected with 20nmol of miR-634 or miR-negative control (NC) in HeLa, KYSE850, or U2OS cells. After 2 days, RNA was extracted, and then expression analysis was performed using agilent microarray. Expression microarray with miR-634 or miR-NC...
ORGANISM(S): Homo sapiens 
2015-08-06 | E-GEOD-71742 | biostudies-arrayexpress
Unknownc-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast cancer gene 1 expression.
Not available
S-EPMC4494910 | biostudies-literature
TranscriptomicsTrophoblast-Induced Changes in C-X-C Motif Chemokine 10 Expression Contribute to Vascular Smooth Muscle Cell Dedifferentiation During Spiral Artery Remodeling
Endothelial cell and vascular smooth muscle cell were cocultured in hanging droplets to form spheroids representing an inverted vessel lumen. Control or conditioned media from an extravillous trophoblast (EVT) cell line was incubated with vascular spheroids for 24 hours. Spheroid RNA was then analyz...
ORGANISM(S): Homo sapiens 
2013-02-17 | E-MTAB-1462 | biostudies-arrayexpress
TranscriptomicsIdentification of Differential Gene Expression During Transition of Bovine Corpus Luteum from Early To Mid–Phase.
Prostaglandin F2 alpha (PGF2alpha) brings about regression of the bovine corpus luteum (CL). This luteolytic property of PGF2alpha is used in the beef and dairy cattle to synchronize estrus. A limitation of this protocol is an insensitivity of the early CL to luteolytic actions of PGF2alpha. The mec...
ORGANISM(S): Bos taurus 
2010-05-05 | E-GEOD-10662 | biostudies-arrayexpress
TranscriptomicsSessile burkholderia cepacia complex cells survive antibiotic treatment by avoiding production of reactive oxygen species
In the present study we wanted to investigate the molecular mechanisms responsible for the tobramycin tolerance in Burkholderia cenocepacia J2315 biofilms.
ORGANISM(S): Burkholderia cenocepacia 
2012-02-01 | E-MEXP-3532 | biostudies-arrayexpress
UnknownFGF13 modulates the gating properties of the cardiac sodium channel Nav1.5 in an isoform-specific manner.
Not available
S-EPMC4988462 | biostudies-literature
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