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TranscriptomicsTranscription Response by sulfur chemolithoautotroph Thiomicrospira crunogenato dissolved inorganic carbon and ammonia limitation
The hydrothermal vent gammaproteobacterium Thiomicrospira crunogena inhabits an unstable environment and must endure dramatic sweeps in habitat chemistry. This sulfur chemolithoautotroph responds to changes in dissolved inorganic carbon (DIC; = CO2 + HCO3- + CO3-2) availability with a carbon concent...
ORGANISM(S): Thiomicrospira crunogena 
2012-03-04 | E-GEOD-36254 | biostudies-arrayexpress
TranscriptomicsCultured chicken embryonic hepatocytes (CEH) exposed to linear PFOS (L-PFOS) or technical-grade PFOS (T-PFOS)
Recently it was discovered that the perfluorooctane sulfonate (PFOS) detected in wildlife, such as fish-eating birds, had a greater proportion of linear PFOS (L-PFOS) than the manufactured technical product (T-PFOS), which contains linear and branched isomers. This suggests toxicological studies bas...
ORGANISM(S): Gallus gallus 
2011-10-28 | E-GEOD-33291 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat 3Y1 embryonic fibroblasts to identify MUC1-induced transcriptional alterations
The MUC1 oncoprotein is aberrantly overexpressed in diverse human malignancies including breast and lung cancer. Although MUC1 modulates the activity of several transcription factors, there is no information regarding the effects of MUC1 on global gene expression patterns and the potential role of M...
ORGANISM(S): Rattus norvegicus 
2009-04-19 | E-GEOD-14337 | biostudies-arrayexpress
UnknownAnalysis of sodium phenylbutyrate and taurursodiol survival effect in ALS using external controls.
Not available
S-EPMC10723227 | biostudies-literature
UnknownMethadone in combination with magnesium, ketamine, lidocaine, and dexmedetomidine improves postoperative outcomes after coronary artery bypass grafting: an observational multicentre study.
Not available
S-EPMC11202251 | biostudies-literature
UnknownHigh Throughput and Computational Repurposing for Neglected Diseases.
Not available
S-EPMC6792295 | biostudies-literature
ProteomicsMITOMICS: defining mitochondrial protein functions through deep multi-omic profiling
Mitochondria are epicenters of eukaryotic metabolism and bioenergetics. Pioneering efforts in recent decades have established the core protein componentry of these organelles and have linked their dysfunction to over 150 distinct disorders. However, hundreds of mitochondrial proteins still lack clea...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-11 | MSV000086685 | MassIVE
TranscriptomicsRestoration and reinforcement of acclimatizing responses during the adaptation of an unfit, metabolically engineered strain
Organisms cope with physiological stressors through acclimatizing mechanisms in the short-term, and through adaptive mechanisms over evolutionary timescales. Whereas the former offer a consistent and largely predictable buffer against stressors, myriad paths of adaptation are often possible. Our wor...
ORGANISM(S): Methylobacterium extorquens AM1 
2012-11-08 | E-GEOD-42116 | biostudies-arrayexpress
ProteomicsEnhanced Characterization of Lysine-Linked Antibody Drug Conjugates Enabled by Middle-Down Mass Spectrometry
HCD Triggered UVPD and EThcD files for characterization of trastuzumab-emtansine (T-DM1)
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-03 | MSV000092585 | MassIVE
MetabolomicsGNPS - MITOMICS: defining mitochondrial protein functions through deep multi-omic profiling
Mitochondria are epicenters of eukaryotic metabolism and bioenergetics. Pioneering efforts in recent decades have established the core protein componentry of these organelles and have linked their dysfunction to over 150 distinct disorders. However, hundreds of mitochondrial proteins still lack clea...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-11 | MSV000086685 | GNPS
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