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UnknownStriatin is a novel modulator of cell adhesion.
Not available
S-EPMC6988865 | biostudies-literature
TranscriptomicsMicroRNA expression in the newborn mouse cochlea and vestibule
MicroRNAs (miRNAs) inhibit the translation of target mRNAs and affect, directly or indirectly, the expression of a large portion of the protein-coding genes. This study focuses on miRNAs that are expressed in the mouse cochlea and vestibule, the two inner ear compartments. To identify miRNAs that ar...
ORGANISM(S): Mus musculus 
2010-06-20 | E-GEOD-15496 | biostudies-arrayexpress
TranscriptomicsTime course expression study in the rat superior olivary complex
The superior olivary complex (SOC) is a prominent auditory brainstem center and represents one of the prime model systems to study the development of sensory circuits. We recently performed genome-wide microarray studies to analyze the SOC-related genetic program at postnatal day (P)4 and P25. Here,...
ORGANISM(S): Rattus norvegicus 
2013-07-31 | E-GEOD-34003 | biostudies-arrayexpress
ProteomicsInner ear proteomics/transcriptomics
The correlation between expression levels of mRNA and protein in mammals is relatively low, with a Pearson correlation coefficient of ~0.40. Post transcriptional regulation contributes to this low correlation. Across taxa, it was demonstrated that translation efficiency, i.e. the protein-to-mRNA rat...
ORGANISM(S): Mus musculus (Mouse) 
2017-04-24 | PXD003379 | Pride
Vestibule Ear Protein Correlation Cochlea Mrna 
UnknownA homozygous AP3D1 missense variant in patients with sensorineural hearing loss as the leading manifestation.
Not available
S-EPMC10449960 | biostudies-literature
TranscriptomicsComparative microarray analyses between the rat superior olivary complex and the brain
To investigate the participation of deafness genes in the genetic program of the superior olivary complex (SOC), a prominent auditory brainstem center, we performed a comparative genome-wide microarray based gene expression analysis of the rat SOC and the rat brain at postnatal days (P) P4 and P25. ...
ORGANISM(S): Rattus norvegicus 
2013-07-31 | E-GEOD-16764 | biostudies-arrayexpress
TranscriptomicsRat superior olivary complex
The superior olivary complex (SOC) is an essential auditory brainstem structure involved in sound localization. In order to identify the genetic program underlying its maturation, we profiled the transcriptome of the rat SOC at postnatal days (P)0, P4, P16, and P25, using genome-wide microarrays (41...
ORGANISM(S): Rattus norvegicus 
2013-07-31 | E-GEOD-36470 | biostudies-arrayexpress
UnknownGJB2 mutations and degree of hearing loss: a multicenter study.
Not available
S-EPMC1285178 | biostudies-literature
UnknownA synonymous variant in MYO15A enriched in the Ashkenazi Jewish population causes autosomal recessive hearing loss due to abnormal splicing.
Not available
S-EPMC8187401 | biostudies-literature
UnknownDisease-specific ACMG/AMP guidelines improve sequence variant interpretation for hearing loss.
Not available
S-EPMC8556313 | biostudies-literature
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