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ProteomicsAutophagy lipidation machinery regulates microtubule dynamics to maintain axonal homeostasis
Axon integrity is crucial for neuronal function. To maintain axonal homeostasis neurons have evolved a unique organization of the microtubule (MT) cytoskeleton, which supports axonal morphology and provides tracks for intracellular transport. Although abnormal MT-based trafficking highlights the pat...
ORGANISM(S): Mus musculus (Mouse) 
2020-03-25 | PXD011279 | Pride
Microtubule dynamics Neuron Autophagy Lc3 Axonal homoeostasis 
UnknownActivation of GSK-3 disrupts cholinergic homoeostasis in nucleus basalis of Meynert and frontal cortex of rats.
Not available
S-EPMC5706587 | biostudies-literature
UnknownMutant TDP-43 drives impairments in axonal transport and glycolysis in a mouse stem-cell-derived motor neuron model of amyotrophic lateral sclerosis (ALS).
Not available
S-EPMC12877184 | biostudies-literature
TranscriptomicsTranscription profiling of fission yeast in response to changes in copper and iron levels
Recent studies in comparative genomics demonstrate that inter-species comparisons represent a powerful tool for revealing both conserved and specialized biological processes across large evolutionary distances. All cells need to adjust to environmental fluctuations in metal levels since both metal ...
ORGANISM(S): Schizosaccharomyces pombe 
2007-03-01 | E-TABM-120 | biostudies-arrayexpress
UnknownAutophagy induction stabilizes microtubules and promotes axon regeneration after spinal cord injury.
Not available
S-EPMC5056063 | biostudies-literature
UnknownBasic fibroblast growth factor accelerates myelin debris clearance through activating autophagy to facilitate early peripheral nerve regeneration.
Not available
S-EPMC7933946 | biostudies-literature
UnknownNovel genes associated with amyotrophic lateral sclerosis: diagnostic and clinical implications.
Not available
S-EPMC5901717 | biostudies-literature
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