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GenomicsMHCC97H, HEP3B AND Huh7 UT, AZD8055 or AZD8055 + Compound #57
MHCC97H, HEP3B AND Huh7 UT, AZD8055 or AZD8055 + Compound #57
PRJNA900588 | ENA
ProteomicsA systematic phosphoproteome screen to identify targets of the Target of Rapamycin (TOR) kinase in Arabidopsis thaliana
The target of rapamycin (TOR) kinase is a central regulatory hub that translates environmental and nutritional information into permissive or restrictive growth decisions. Although the TOR pathway is conserved among eukaryotes, plants developed unique adaptations to this pathway to cope with their a...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-07-17 | PXD008355 | Pride
Arabidopsis Sucrose Azd8055 Target of rapamycin (tor) Cell culture Label-free quantitative ms Phosphoproteomics Rapamycin 
ProteomicsChemical inhibition of the target of rapamycin kinase in Chlamydomonas reinhardtii leads to rapid cysteine oxidation and sustained physiological changes.
The target of rapamycin (TOR) kinase is a key metabolic regulator with a role in diverse processes, including nutritional sensing, protein translation, and autophagy. In the green alga Chlamydomonas reinhardtii, TOR maintains these responsibilities and is additionally linked to the regulation of inc...
ORGANISM(S): Chlamydomonas reinhardtii 
2019-10-04 | PXD014819 | Pride
Azd8055 Global proteomics Chlamydomonas reinhardtii Target of rapamycin Reversible cysteine oxidation 
UnknownA low dose of AZD8055 enhances radiosensitivity of nasopharyngeal carcinoma cells by activating autophagy and apoptosis.
Not available
S-EPMC6780664 | biostudies-literature
UnknownAZD8055 Is More Effective Than Rapamycin in Inhibiting Proliferation and Promoting Mitochondrial Clearance in Erythroid Differentiation.
Not available
S-EPMC11479778 | biostudies-literature
GenomicsProfiling of bulk and ribosome associated mRNA of Arabidopsis roots upon lateral root induction upon TOR activity inhibition with AZD8055 [dataset2]
Profiling of bulk and ribosome associated mRNA of Arabidopsis roots upon lateral root induction upon TOR activity inhibition with AZD8055 [dataset2]
PRJNA818878 | ENA
UnknownThe mTOR inhibitor AZD8055 overcomes tamoxifen resistance in breast cancer cells by down-regulating HSPB8.
Not available
S-EPMC6289376 | biostudies-literature
UnknownAZD8055 enhances in vivo efficacy of afatinib in chordomas.
Not available
S-EPMC9534552 | biostudies-literature
UnknownPrevention of BMS-777607-induced polyploidy/senescence by mTOR inhibitor AZD8055 sensitizes breast cancer cells to cytotoxic chemotherapeutics.
Not available
S-EPMC5528636 | biostudies-literature
TranscriptomicsProfiling of bulk and ribosome associated mRNA of Arabidopsis roots upon lateral root induction upon TOR activity inhibition with AZD8055 [dataset2]
We performed targeted purification of polysomal mRNA (TRAP-Seq, Vragović et al, 2015 - http://dx.doi.org/10.1073/pnas.1417947112) using a transgenic line ubiquitously expressing a GFP-tagged RPL18 (Mustroph et al, 2009 - https://doi.org/10.1073/pnas.0906131106) 6h after the synchronous induction of ...
ORGANISM(S): Arabidopsis thaliana 
2022-03-23 | GSE199203 | GEO
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