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ProteomicsB-cell compartment hyperactivation in PHIV
Despite a successful antiretroviral therapy (ART), adolescents living with perinatally acquired HIV (PHIV) experience signs of B-cell hyperactivation with expansion of 'namely' atypical B-cell phenotypes, including double negative (CD27-IgD-) and termed age associated (ABCs) B-cells(T-bet+CD11c+), w...
ORGANISM(S): Homo sapiens (Human) 
2022-03-03 | PXD031908 | Pride
Exhausted t-cells Immune activation Cahiv-1 rna Late art T-bet Cd11c Proteomic profiling B-cell hyperactivation Perinatal hiv/aids 
GenomicsIntegrin β3 Deficiency Unleashes Spontaneous Pulmonary Inflammation by Promoting B Cell Hyperactivation via the CD40-CD40L Axis
Integrin β3 Deficiency Unleashes Spontaneous Pulmonary Inflammation by Promoting B Cell Hyperactivation via the CD40-CD40L Axis
PRJNA1414488 | ENA
GenomicsDeletion of Xist repeat B disrupts cell cycle and asymmetric cell division through Usp9x hyperactivation in mice
Deletion of Xist repeat B disrupts cell cycle and asymmetric cell division through Usp9x hyperactivation in mice
PRJNA1166650 | ENA
GenomicsDeletion of Xist repeat B disrupts cell cycle and asymmetric cell division through Usp9x hyperactivation in mice [II]
Deletion of Xist repeat B disrupts cell cycle and asymmetric cell division through Usp9x hyperactivation in mice [II]
PRJNA1166688 | ENA
UnknownAKT Hyperactivation and the Potential of AKT-Targeted Therapy in Diffuse Large B-Cell Lymphoma.
Not available
S-EPMC5530910 | biostudies-literature
UnknownDeterminants of B-Cell Compartment Hyperactivation in European Adolescents Living With Perinatally Acquired HIV-1 After Over 10 Years of Suppressive Therapy.
Not available
S-EPMC9009387 | biostudies-literature
Transcriptomics90 min Met4 hyperactivation ChIP-chip
Identification of in vivo binding targets of Met4 and Met32 by conducting chromatin immunoprecipitation studies using genomic tiling arrays (ChIP-on-chip 4X44K whole yeast genome arrays by Agilent) following 90 minutes Met4 hyperactivation.
ORGANISM(S): Saccharomyces cerevisiae 
2012-02-21 | E-MEXP-3302 | biostudies-arrayexpress
TranscriptomicsIntegrin β3 Deficiency Unleashes Spontaneous Pulmonary Inflammation by Promoting B Cell Hyperactivation via the CD40-CD40L Axis
Background: Pulmonary immune homeostasis relies on stringent control of adaptive immunity. Integrin β3 is a critical mediator of cellular adhesion and platelet function. However, its specific role in modulating adaptive immunity, particularly B cell immune response, remains poorly understood.Results...
ORGANISM(S): Mus musculus 
2026-04-15 | GSE317568 | GEO
UnknownCXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness.
Not available
S-EPMC8478649 | biostudies-literature
UnknownERK hyperactivation in epidermal keratinocytes impairs intercellular adhesion and drives Grover disease pathology.
Not available
S-EPMC11601706 | biostudies-literature
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