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ProteomicsGlobal phospho-proteomics analysis of the effect of CD25 KO in precursor and mature B-cell
To assess the effect of CD25 (Il2ra) knockout on signaling in pre-B leukemia, pre-B cells from CD25-floxed mouse bone marrow were grown ex-vivo with IL-7 and transformed with BCR-ABL1, before treatment with 4-OHT to induce CD25 KO. Phosphoproteomics was performed and differential phosphosites analys...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-23 | PXD038996 | Pride
B-cell pre-b cd25 il2ra phospho-proteomics 
ProteomicsPhospho-Tyrosine analysis of the effect of CD25 KO in pre-B-ALL cells
To assess the effect of CD25 (Il2ra) knockout on signaling in pre-B leukemia, pre-B cells from CD25-floxed mouse bone marrow were grown ex-vivo with IL-7 and transformed with BCR-ABL1, before tratment with 4-OHT to induce CD25 KO. Phospho-Tyrosine proteomics was performed and differential phosphosit...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-23 | PXD036128 | Pride
Bcr-abl1 Mouse Cd25 Il2ra 
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