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TranscriptomicsThe human miRNA repertoire of different blood compounds
Background: MiRNAs from body fluids gain more and more attraction as biomarker candidates. Besides serum, patterns from whole blood are increasingly considered as markers for human pathologies. Usually, the contribution of different cell types to the respective signature remains however unknown. In ...
ORGANISM(S): Homo sapiens 
2014-06-16 | E-GEOD-56590 | biostudies-arrayexpress
TranscriptomicsmiRNA Profiles in lung cancer patients and controls with other non-cancer lung diseases
This project analyzes plasma profiles of patients suffering from lung cancer and controls with other non-cancer lung diseases Analysis of plasma obtained from 26 patients collected at up to 8 time points and from 12 controls
ORGANISM(S): Homo sapiens 
2015-09-24 | E-GEOD-68951 | biostudies-arrayexpress
TranscriptomicsmiRNA profiles of Wilms tumor patients and controls
Blood-borne miRNA signatures have recently been reported for various tumor diseases. Here, we compared the miRNA signature in Wilms tumor patients prior to and after preoperative chemotherapy according to the SIOP protocol 2001. We did not find a significant difference between the miRNA signatures o...
ORGANISM(S): Homo sapiens 
2013-07-22 | E-GEOD-38419 | biostudies-arrayexpress
TranscriptomicsCurcumin intake affects miRNA signature in murine melanoma with mmu-miR-205-5p most significantly altered.
Melanoma is the most aggressive form of skin cancer with estimated 48,000 deaths worldwide. The polyphenol curcumin derived from the plant Curcuma longa is well known for its anti-inflammatory and anti-cancerogenic properties. Accordingly, dietary intake of this compound may be suitable for melanoma...
ORGANISM(S): Mus musculus 
2013-12-31 | E-GEOD-47211 | biostudies-arrayexpress
TranscriptomicsTowards clinical applications of blood-born miRNA signatures: The influence of the anticoagulant EDTA on miRNA abundance
Circulating microRNAs (miRNAs) from blood are increasingly recognized as biomarker candidates for human diseases. Clinical routine settings frequently include blood sampling in tubes with EDTA as anticoagulant without considering the influence of phlebotomy on the overall miRNA expression pattern. W...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-73401 | biostudies-arrayexpress
ProteomicsImmunogenic epitopes of the meningioma-associated antigen TXNDC16
We used customized peptide arrays of 163 TXNDC16 peptides to identify immunogenic TXNDC16 epitopes and asked whether discrimination of meningioma and control sera is possible with a specific subset selection of all immunogenic epitopes. CelluSpotsM-bM-^DM-" peptide arrays were manufactured by Intavi...
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-58949 | biostudies-arrayexpress
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