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ProteomicsComprehensive peptide analysis of mouse brain striatum identifies novel sORF-encoded polypeptides
Bio-active peptides are involved in the regulation of most if not all physiological processes in the body. Classical bio-active peptides (CBAPs) are mostly cleaved from a larger precursor protein and stored in secretion vesicles from which they are released in the extracellular space to exert there ...
ORGANISM(S): Mus musculus (Mouse) 
2018-05-10 | PXD008526 | Pride
5’utr Neuropeptides Peptidomic approach Ribosome profiling Bio-active peptides Sorf Seps 
ProteomicsMultiple solvent elution, a method to counter the effects of Co-Elution and Ion Suppression of peptides in LC-MS analysis.
The abundance of proteins in the cellular proteome ranges from millions of copies to one copy per cell. This wide dynamic range represents a major challenge in proteomic analysis. On average, any human cell type expresses up to approximately 10.000 different protein coding genes that are used to syn...
ORGANISM(S): Homo sapiens (Human) 
2019-06-28 | PXD011908 | Pride
Proteome coverage Co-elution Lc-ms Proteomics Solvents Ion suppression 
MetabolomicsFour layer multi-omics reveals molecular responses to aneuploidy in Leishmania

Aneuploidy causes system-wide disruptions in the stochiometric balances of transcripts, proteins, and metabolites, often resulting in detrimental effects for the organism. The protozoan parasite Leishmania has an unusually high tolerance for aneuploidy, but the molecular and functional consequenc...

2022-09-19 | MTBLS1612 | MetaboLights
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