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ProteomicsIntrinsically Disordered Regions in Chromodomain Helicase DNA-binding (CHD) Proteins Shape Distinct Protein Interaction Networks
Metazoans employ chromodomain helicase DNA-binding (CHD) enzymes to reposition nucleosomal DNA for transcription and replication. The CHD family consists of nine distinct members (CHD1-9) that possess highly conserved chromo and ATPase domains. These domains are flanked by poorly characterised N- an...
ORGANISM(S): Homo sapiens (Human) 
2025-05-26 | PXD055009 | Pride
Dna helicase Chromatin remodelers Transcription Intrinsically disordered regions Aggregation prone regions Protein-protein interactions 
GenomicsCarroll_ChIP_exo
This experiment validates the ChIP-exo protocol on the Illumina sequencing platform.
ORGANISM(S): Homo sapiens 
2014-01-15 | E-MTAB-1827 | biostudies-arrayexpress
MetabolomicsNicotinamide Riboside is Uniquely Bioavailable in People and Mice
Nicotinamide riboside (NR) is in wide use as an NAD+ precursor vitamin. Here we conducted experiments to determine the time and dose-dependent effects of NR on blood, liver and heart NAD+ metabolism in people and mice. We report that human blood cell NAD+ can rise as much as 2.7-fold with a single d...
2016-09-09 | MTBLS368 | MetaboLights
TranscriptomicsExpression data from WT, MPK6 Overexpression, and mpk6 T-DNA knockout Arabidopsis root and shoot under hypoxic and mock conditions
MPK6 shows transient increase in activity under hypoxia with maximal activity at 2 hrs. To study the role of MPK6 in hypoxia in Arabidopsis, 10 do seedlings of WT, mpk6 and MPK6 plants were exposed to 2 hrs hypoxia and 2hr air (mock). Because there are no major phenotypic differences between the ge...
ORGANISM(S): Arabidopsis thaliana 
2011-12-03 | E-GEOD-31158 | biostudies-arrayexpress
UnknownDevelopment and validation of a federated learning framework for detection of subphenotypes of multisystem inflammatory syndrome in children.
Not available
S-EPMC10854314 | biostudies-literature
TranscriptomicsTranscription profiling by array of mouse kidneys following chronic ACTH treatment or control treatment
This experiment compares gene expression in kidneys of control and ACTH treated mice.
Kidney RNA was prepared from 6 mice: three controls and three ACTH treated and processed by the microarray team at Ark Genomics and the Roslin Institute.
RNAs were processed through standard Affymetrix prot...
ORGANISM(S): Mus musculus 
2009-03-31 | E-MEXP-1761 | biostudies-arrayexpress
UnknownPerceptions, use and attitudes of pharmacy customers on complementary medicines and pharmacy practice.
Not available
S-EPMC2919443 | biostudies-literature
TranscriptomicsConsequences of GATA1 expression in Gata1- G1ME Murine Megakaryocyte/Erythrocyte Progenitor Cell Line
G1ME cells are GATA1-deficient murine bipotential megakaryocyte/erythrocyte progenitor cells derived from Gata1-negative murine ES cells. In order to assess the impact of GATA1 on gene regulation and cell differentiation, an expression construct was used to transiently produce high levels of GATA1....
ORGANISM(S): Mus musculus 
2009-06-10 | E-GEOD-14980 | biostudies-arrayexpress
UnknownIntravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.
Not available
S-EPMC10600726 | biostudies-literature
UnknownStress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients.
Not available
S-EPMC9682690 | biostudies-literature
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