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TranscriptomicsTranscription profiling of Drosophila developmental time series
Michelle N. Arbeitman, Eileen E. M. Furlong, Farhad Imam, Eric Johnson, Brian H. Null, Bruce S. Baker, Mark A. Krasnow, Matthew P. Scott, Ronald W. Davis and Kevin P. White. Gene Expression During the Life Cycle of Drosophila melanogaster, Science, 297: 2270-2275, 2002. This work can be accessed fro...
ORGANISM(S): Drosophila melanogaster 
2004-11-06 | E-FLYC-6 | biostudies-arrayexpress
TranscriptomicsPKC1 cell cycle study
Transcriptional profiling of a Saccharomyces cerevisiae protein kinase Pkc1p temperature sensitive mutant on cells synchronised in S phase and then released. The Mcm1p-Fkh2p-Ndd1p complex in Saccharomyces cerevisiae controls the cyclical expression of the CLB2 cluster of genes at the G2/M phase tran...
ORGANISM(S): Saccharomyces cerevisiae 
2013-03-14 | E-MEXP-3667 | biostudies-arrayexpress
TranscriptomicsYeast expression data from conditions that inhibit sirtuins
Sir2 is an NAD+-dependent histone deacetylase, and is the founding member of a large, phylogentically conserved, family of such deacetylases called the Sirtuins. The budding yeast, Saccharomyces cerevisiae, harbors 4 paralogs of Sir2, known as Hst1, Hst2, Hst3, and Hst4. Reducing the intracellular N...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-10 | E-GEOD-18488 | biostudies-arrayexpress
TranscriptomicsLoss of DNA replication control is a potent initiator of gene amplification
Eukaryotic cells use numerous mechanisms to ensure that no segment of their DNA is re-replicated within a single cell cycle. Despite longstanding speculation that such tight regulation is needed to protect cells from genomic alterations, this notion has never been experimentally tested. Here we show...
ORGANISM(S): Saccharomyces cerevisiae 
2011-05-17 | E-GEOD-22018 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of H3K4 methylation
This SuperSeries is composed of the following subset Series: GSE18261: Expression analysis on Mll1+/+ and Mll1-/- MEFs GSE18262: ChIP-chip with antibodies for histone 3 lysine 4 trimethylation and histone 3 in Mll1+/+ and Mll1-/- MEFs GSE18263: ChIP-chip with antibodies for histone 3 lysine 4 trimet...
ORGANISM(S): Mus musculus 
2009-10-20 | E-GEOD-18258 | biostudies-arrayexpress
TranscriptomicsAgricultural sterol biosynthesis inhibitor fungicides
Resistance to agricultural fungicides in the field has created a need for discovering fungicides with new modes of action. DNA microarrays, because they provide information on expression of many genes simultaneously, could help to identify the modes of action. To begin an expression pattern database...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-10 | E-GEOD-2412 | biostudies-arrayexpress
TranscriptomicsExpression analysis on Mll1+/+ and Mll1-/- MEFs
Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II A common landmark of activated genes is the presence of trimethylation on lysine 4 of histone H3 (H3K4) ...
ORGANISM(S): Mus musculus 
2009-10-20 | E-GEOD-18261 | biostudies-arrayexpress
TranscriptomicsChIP-chip with antibodies for histone 3 lysine 4 trimethylation, histone 3, and PolII in Mll1+/+ and Mll1-/- MEFs
Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II A common landmark of activated genes is the presence of trimethylation on lysine 4 of histone H3 (H3K4) ...
ORGANISM(S): Mus musculus 
2010-06-21 | E-GEOD-18264 | biostudies-arrayexpress
UnknownDesign and Baseline Characteristics of the Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease Trial.
Not available
S-EPMC6889917 | biostudies-literature
UnknownFinerenone in Patients With Chronic Kidney Disease and Type 2 Diabetes by Sodium-Glucose Cotransporter 2 Inhibitor Treatment: The FIDELITY Analysis.
Not available
S-EPMC9862372 | biostudies-literature
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