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TranscriptomicsTranscription profiling of S. cerevisiae wild type versus delta vts1
The experiment was designed to look for genes up/downregulated in the absense of Vts1p compared to wild-type cells grown in steady state conditions. Experiment Overall Design: 3 chips delta VTS1 vs. 2 wild type control chips
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-12 | E-GEOD-3859 | biostudies-arrayexpress
UnknownNon-canonical active site architecture of the radical SAM thiamin pyrimidine synthase.
Not available
S-EPMC4389238 | biostudies-literature
TranscriptomicsGlobal phenotypic and genomic comparison of two Saccharomyces cerevisiae wine strains
The aim of this study is to phenotype a collection of 27 S. cerevisiae commercial wine strains growing within temperatures (4-45ºC) in both minimal media (SD) and synthetic must (SM) and, taking into account µmax value, to select two strains with divergent phenotype in their capacity to grow at low ...
ORGANISM(S): Saccharomyces cerevisiae 
2015-03-31 | E-GEOD-60140 | biostudies-arrayexpress
Transcriptomics3' RNA-Seq (3'SEQ) analysis gene expression profiling at G1-S transition in human embryonic stem cells (hESCs) and hESC-derived endoderm cells
In this report, we examine transcripts on a genome-wide level between the synchronized cell cycles of hESCs and hESC-derived endoderm cells. We found 10347, 10299 and 10362 genes expressed in the G1, G1/S, and S phase of hESCs, respectively; 10333, 10227 and 10215 genes expressed at the G1, G1/S and...
ORGANISM(S): Homo sapiens 
2014-05-14 | E-GEOD-47117 | biostudies-arrayexpress
TranscriptomicsMicroRNAs are amplifiers of monocyte inflammatory networks and repressors of metabolism
MicroRNAs are amplifiers of monocyte inflammatory networks and repressors of metabolism Milk and blood isolated CD14+ monocyte cells taken from 5 infected Holstein friesians and 5 control Holstein friesians. Five animal infected with live S. uberis, cells extracted at 0, 12, 24, 36, and 48 hours pos...
ORGANISM(S): Bos taurus 
2014-07-03 | E-GEOD-51848 | biostudies-arrayexpress
TranscriptomicsEngineering acetyl-CoA supply: Functional expression of a bacterial pyruvate-dehydrogenase complex in the cytosol of Saccharomyces cerevisiae
The energetic (ATP) cost of biochemical pathways critically determines the maximum yield of metabolites of vital or commercial relevance. Cytosolic acetyl-CoA is a key precursor for biosynthesis in eukaryotes and for many industrially relevant product pathways that have been introduced into Saccharo...
ORGANISM(S): Saccharomyces cerevisiae 
2014-11-04 | E-GEOD-59814 | biostudies-arrayexpress
TranscriptomicsEngineering topology and kinetics of sucrose metabolism in Saccharomyces cerevisiae for improved ethanol yield
Sucrose is a major carbon source for industrial bioethanol production by Saccharomyces cerevisiae. In yeasts, two modes of sucrose metabolism occur: (i) extracellular hydrolysis by invertase, followed by uptake and metabolism of glucose and fructose, and (ii) uptake via sucrose-H+ symport followed b...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-05 | E-GEOD-30535 | biostudies-arrayexpress
TranscriptomicsStructural and functional characterization of the N-terminus of Schizosaccharomyces pombe Cwf10
The spliceosome is a dynamic macromolecular machine that catalyzes the removal of introns from pre-mRNA to make mature message. Schizosaccharomyces pombe Cwf10 (homolog Saccharomyces cerevisiae Snu114 and of Human U5-116K), an integral member of the U5 snRNP, is a GTPase that shares sequence homolog...
ORGANISM(S): Schizosaccharomyces pombe 
2013-09-25 | E-GEOD-47573 | biostudies-arrayexpress
GenomicsSpo11-oligo mapping in bas1 and ino4 mutants
Meiotic recombination is initiated by developmentally programmed DNA double-strand breaks (DSBs). In S. cerevisiae, the vast majority of DSBs occur in the nucleosome-depleted regions at gene promoters, where transcription factors (TFs) bind. It has been proposed that TF binding can stimulate DSB for...
ORGANISM(S): Saccharomyces cerevisiae 
2015-08-21 | E-GEOD-67910 | biostudies-arrayexpress
TranscriptomicsMicroRNA regulation of the bovine local and systemic monocyte transcriptional responses to an in vivo Streptococcus uberis challenge
MicroRNA regulation of the bovine local and systemic monocyte transcriptional responses to an in vivo Streptococcus uberis challenge Milk and blood isolated CD14+ monocyte cells taken from 5 infected Holstein friesians and 5 control Holstein friesians. Five animal infected with live S. uberis, cells...
ORGANISM(S): Bos taurus 
2014-07-03 | E-GEOD-51856 | biostudies-arrayexpress
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