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ProteomicsEffects of lysine deacetylase inhibitor treatment on LPS responses of alveolar-like macrophages
Macrophages are key immune cells in tissues that are able to adapt their metabolic phenotype in response to different stimuli. Lysine deacetylases are important enzymes for regulating inflammatory gene expression and their inhibitors have anti-inflammatory effects in models of chronic obstructive pu...
ORGANISM(S): Mus musculus (Mouse) 
2024-02-21 | PXD040933 | Pride
Dia proteomics Alveolar-like macrophages Lps activation Kdac inhibition Mouse 
ProteomicsA Polyamine-mediated Posttranslational Modification Required For Macrophage Tissue Residency – Differential proteome analysis of DHPS deficient macrophages
Tissue resident macrophages (MTRs) regulate tissue repair and homeostasis by clearing cell debris, and are thought to form the first line of defense against pathogens. MTRs form early in life and self-renew locally. However, during tissue damage or disease, bone-marrow derived monocytes enter tissue...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-23 | PXD054670 | Pride
Eif5a Dia Spectronaut Dda spectral library Tissue resident macrophage proteomics Maxquant Label-free quantification Deoxyhypusine synthase (dhps) Hypusine 
UnknownNovel staphylococcal glycosyltransferases SdgA and SdgB mediate immunogenicity and protection of virulence-associated cell wall proteins.
Not available
S-EPMC3794999 | biostudies-literature
UnknownMachine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score.
Not available
S-EPMC8344569 | biostudies-literature
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