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TranscriptomicsPhloridzin reduces blood glucose levels and alters hepatic gene expression in normal BALB/c mice
We previously showed that a diet containing phloridzin suppressed the blood glucose levels in streptozotocin-induced diabetic mice most likely by inhibiting glucose absorption from the small intestine. In this study, we showed that 0.5% and 1% phloridzin diets significantly reduce the blood glucose ...
ORGANISM(S): Mus musculus 
2012-05-17 | E-GEOD-37415 | biostudies-arrayexpress
TranscriptomicsMethylation profiling of differentially expressed regions between C57BL/6 and BALB/c in bone marrow derived macrophages
DNA-methylation is a vital epigenetic mark that participates in establishing and maintaining chromatin structures and in regulating gene transcription during mammalian development and cellular differentiation. Inter-individual differences in methylation patterns may represent a major source of pheno...
ORGANISM(S): Mus musculus 
2010-05-15 | E-GEOD-14463 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse intestine: C57Bl/6 MTHFR+/- vs BALB/c MTHFR+/-
Previous studies in our laboratory have shown that low folate diet (control diet with 2mg folate/kg, low folate diet with 0.3mg folate/kg) can induce intestinal tumors in BALB/c mice. In addition, we reported that C57Bl/6J mice did not form tumors under the same conditions. We used microarrays to id...
ORGANISM(S): Mus musculus 
2013-04-09 | E-GEOD-34010 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of 4 week old BALB/c_Fech m1Pas mice (Fech) vs with 4 week old control BALB/c mice
Comparison of liver gene expression of 4 week old BALB/c_Fech m1Pas mice(Fech mice for short) with 4 week old control BALB/c mice.
ORGANISM(S): Mus musculus 
2005-10-21 | E-MEXP-194 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse intestine: BALB/c MTHFR+/+ on control diet vs BALB/c MTHFR+/- on folate deficient diet
Previous studies in our laboratory have shown that low folate diet (control diet with 2mg folate/kg, low folate diet with 0.3mg folate/kg) can induce intestinal tumors in BALB/c mice. We used microarrays to compare MTHFR+/+ BALB/c mice fed control diet and MTHFR+/- BALB/c mice fed low folate diet. ...
ORGANISM(S): Mus musculus 
2013-12-03 | E-GEOD-34011 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of male Fech mutant BALB/c mouse livers vs male control BALB/c livers
Comparison of gene expression in livers of male Fech mutant BALB/c mouse with livers of male control BALB/c
ORGANISM(S): Mus musculus 
2005-10-14 | E-MEXP-189 | biostudies-arrayexpress
TranscriptomicsComparison of bone marrow-derived macrophages from BALB/c and C57BL/6 mice with and without interferon-gamma stimulation.
ABSTRACT Macrophages are essential components of the innate immune system and crucial for pathogen elimination in early stages of infection. We previously observed that bone marrow-derived macrophages (BMM) from C57BL/6 mice exhibited increased killing activity against Burkholderia pseudomallei comp...
ORGANISM(S): Mus musculus 
2014-04-15 | E-GEOD-39349 | biostudies-arrayexpress
MetabolomicsGlobal Metabolomic Profiling of Mice Brains following Experimental Infection with the Cyst-Forming Toxoplasma gondii
The interplay between the Apicomplexan parasite Toxoplasma gondii and its host has been largely studied. However, molecular changes at the metabolic level in the host central nervous system and pathogenesis-associated metabolites during brain infection are largely unexplored. We used a global metabo...
2017-01-27 | MTBLS217 | MetaboLights
MetabolomicsMetabolomic Profiling of Mice Serum during Toxoplasmosis Progression Using Liquid Chromatography-Mass Spectrometry
Better understanding of the molecular changes associated with disease is essential for identifying new routes to improved therapeutics and diagnostic tests. The aim of this study was to investigate the dynamic changes in the metabolic profile of mouse sera during T. gondii infection. We carried out ...
2017-01-25 | MTBLS216 | MetaboLights
TranscriptomicsHepatic gene expression in BALB/c mice fed a quercetin diet
We showed that diets containing 0.1% or 0.5% quercetin lowered the STZ-induced increase in blood glucose levels and improved plasma insulin levels. A cluster analysis of the hepatic gene expressions showed that 0.5% quercetin diet suppressed STZ-induced alteration of gene expression. Gene set enri...
ORGANISM(S): Mus musculus 
2012-05-29 | E-GEOD-38136 | biostudies-arrayexpress
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