Ball Claudia R CR

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Transcriptomics (2)
Proteomics (2)

Organisms

Homo sapiens (2)
uncultured zooxanthellae Symbiodinium (2)
Alytes obstetricans (2)
Anemonia sulcata (2)
Oryza sativa Indica Group x Oryza nivara (2)
Mycobacteroides abscessus subsp. abscessus (2)
Stichodactyla haddoni (2)
Mesomycoplasma hyorhinis SK76 (2)
Geobacter (2)
Enterococcus faecium DO (2)
Gorilla gorilla (2)
Hyphomicrobium sp. MC8b (2)
Lodderomyces parapsilosis (2)
[Candida] boidinii (2)
Heliocidaris erythrogramma (2)
Saccharomycopsis capsularis (2)
Citeromyces matritensis (2)
Pachysolen tannophilus (2)
Tortispora caseinolytica (2)
Peterozyma xylosa (2)
Ambrosiozyma philentoma (2)
Campylobacter jejuni subsp. jejuni ATCC 33560 (2)
Nakazawaea wickerhamii (2)
fungal sp. 5OL6-6PL1 (2)
Babjeviella inositovora (2)
Campylobacter coli RM2228 (2)
Ascoidea rubescens (2)
Saturnispora dispora (2)
Lipomyces starkeyi (2)
Synechococcus sp. WH 8012 (2)

Repository

biostudies-arrayexpress (2)
pride (2)

Tissue

Breast epithelial cell (1)
Breast epithelium (1)
Stem cell (1)

Disease

Colorectal cancer (1)
Sarcoma (1)

Technology Type

Mass Spectrometry (2)
Shotgun proteomics (2)

Instrument Platform

Illumina NovaSeq 6000 (2)

Publication Date

2022 (2)
2023 (1)
2021 (1)

Study type

RNA-seq of non coding RNA from single cells (1)
ScATAC-seq (1)

Release Date

2022 (2)

Lab affiliation

Division of Applied Functional Genomics, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), NCT Heidelberg, Germany (1)
NCT Dresden (1)

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Functional states in tumor-initiating cell differentiation in human colorectal cancer

Intra-tumor heterogeneity of tumor-initiating cell (TIC) activity drives colorectal cancer (CRC) progression and therapy resistance. Here, we used single-cell mRNA-sequencing (scRNA-seq) of patient-derived CRC models to decipher distinct cell subpopulations based on their transcriptional profiles. C...

ORGANISM(S): Homo sapiens (Human)

2021-05-07 | PXD018230 | Pride

Multi-Omic and Functional Analysis for Classification and Treatment of Sarcomas with FUS-TFCP2 or EWSR1-TFCP2 Fusions

Linking clinical multi-omics analyses with mechanistic studies may improve the understanding of rare cancers. We leveraged two precision oncology programs to investigate rhabdomyosarcoma with FUS/EWSR1-TFCP2 fusions, an orphan malignancy without effective therapies. All tumors exhibited outlier ALK ...

ORGANISM(S): Homo sapiens (Human)

2023-11-13 | PXD045522 | Pride

Alk Fus-tfcp2 Sarcoma Ewsr1-tfcp2

Multiomic (Joint snRNA/snATAC) sequencing data of intestinal crypts and epithelial only organoids derived from human fetal duodenum

Here, we used joint single-nuclei RNA-sequencing (snRNA-seq) and single-nuclei ATAC sequencing (scATAC) to profile freshly isolated crypts from the human fetal intestine and matched intestinal epithelial only organoids (also known as enteroids) derived from these crypts after one passage of in vitro...

ORGANISM(S): Homo sapiens

2022-07-16 | E-MTAB-11908 | biostudies-arrayexpress

scRNA-seq of intestinal epithelial organoids derived from human fetal duodenum

Here, we used single-cell RNA-sequencing (scRNA-seq) to profile intestinal epithelial only organoids (also known as enteroids) from human fetal duodenum after one passage of in vitro growth. Organoids were grown in the standard 25% LWRN media with either 100 ng/ml of EGF or 1 ng/ml of EREG added.