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TranscriptomicsEffect of a High Phosphorus Diet on Hepatic Gene Expressions in Rat
A high phosphorus (HP) diet causes disorders of renal function, bone metabolism, and vascular function. We previously demonstrated that DNA microarray analysis is an appropriate method to comprehensively evaluate the effects of a HP diet on kidney dysfunction such as calcification, fibrillization, a...
ORGANISM(S): Rattus norvegicus 
2016-05-18 | E-GEOD-71201 | biostudies-arrayexpress
ProteomicsPeriodontal pathogen induces entero-hepatic metabolic derangements in type 2 diabetic mouse model
This is the first report of the metabolic and metaproteomic integrated changes in the gut and liver by the swallowed periodontopathogen. Periodontal disease pathogen Porphyromonas gingivalis are observed in faeces as peptides level in proteomic analysis and make changes in bowel microbial compositio...
ORGANISM(S): Cellular Organisms 
2021-09-21 | PXD021851 | JPOST Repository
ProteomicsChronic high glucose condition reduced expressions of intercellular adhesion molecules and increased intercellular hyperpermeability in periodontal epithelium.
There is a close relationship between hyperglycemia in diabetes and progression of periodontal disease. This study aims to investigate the effect of hyperglycemia on the barrier function of gingival epithelial cells as a cause of hyperglycemia-exacerbated periodontitis in diabetes mellitus. Abnormal...
ORGANISM(S): Mus Musculus (mouse) 
2023-07-29 | PXD035613 | JPOST Repository
ProteomicsPhosphoproteome data of WT and ob/ob mice liver during starvation
Ten-week-old male mice (WT and ob/ob) were starved for 0, 2, 4, 6, 8, 12, 16, and 24 hours and liver samples were collected. Total proteins extracted during sample preparation of metabolomic analysis were subjected to the following phosphoproteomic analysis. As described above, 2 mg of protein solut...
ORGANISM(S): Mus Musculus (mouse) 
2025-05-20 | PXD053026 | JPOST Repository
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