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UnknownEfficacy and Safety of Dupilumab in Adults with Prurigo Nodularis with or Without Atopic Comorbidities: A Subgroup Analysis from Two Randomized Phase III Clinical Trials.
Not available
S-EPMC12860806 | biostudies-literature
UnknownDupilumab in patients with prurigo nodularis: two randomized, double-blind, placebo-controlled phase 3 trials.
Not available
S-EPMC10202800 | biostudies-literature
TranscriptomicsHuman epithelial cell response to bacterial signal indole
Indole is a bacterial signal secreted by pathogenic and commensal Escherichia coli in the stationary phase at high concentrations (~600 µM). Prior work from our lab has shown that indole decreases E. coli O157:H7 (EHEC) chemotaxis, motility, attachment to epithelial cells and biofilm formation. How...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-14379 | biostudies-arrayexpress
TranscriptomicsLarge-scale downregulation of cytokeratins in amniotic epithelium after Group B Streptococcus choriodecidual infection in Macaca nemestrina: a pathway to PPROM
Early events leading to intrauterine infection remain poorly defined, but may hold the key to a therapeutic intervention for preterm delivery. To determine early molecular pathways associated with membrane weakening that may progress to preterm premature rupture of membranes (PPROM), we examined th...
ORGANISM(S): Macaca nemestrina 
2014-11-18 | E-GEOD-46290 | biostudies-arrayexpress
TranscriptomicsOvarian Cancer Dataset
Background. Genome-wide expression changes are associated with development of chemoresistance in patients with ovarian cancer (OVCA); the BCL2 antagonist of cell death (BAD) apoptosis pathway may play a role in clinical outcome. Methods. We analyzed specimens and/or genomic data from 1,406 patients...
ORGANISM(S): Homo sapiens 
2011-10-02 | E-GEOD-23554 | biostudies-arrayexpress
TranscriptomicsChanges in EHEC virulence on exposure to epithelial cell secreted factors
EHEC is a food-borne pathogen that colonizes human GI tract and leads to infection. To understand the process of colonization and to decipher if any factors secreted by intestinal epithelial cells help EHEC during the infection process, we studied expression of EHEC virulence gene expression when ex...
ORGANISM(S): Escherichia coli O157:H7 str. EDL933 
2012-10-04 | E-GEOD-22285 | biostudies-arrayexpress
TranscriptomicsGenomic encoding of transcriptional burst kinetics
We used single-cell RNA-sequencing to generate allele-resolution expression levels in individual cells that we used for inference of transcriptional burst kinetics.
ORGANISM(S): Mus musculus 
2018-09-30 | E-MTAB-6362 | biostudies-arrayexpress
TranscriptomicsGene expression changes with induction of in-vitro platinum-resistance in ovarian cancer cell lines.
We treated 8 human ovarian cancer cell lines with cisplatin in treatment/recovery cycles to induce in-vitro resistance to the drug. Microarrays measured gene expression at baseline and after each dose schedule (after recovery). OVCA cells lines (T8, OVCAR5, OV2008, IGROV1, C13, A2780S, A2780CP, and ...
ORGANISM(S): Homo sapiens 
2011-10-02 | E-GEOD-23553 | biostudies-arrayexpress
TranscriptomicsGene expression in ovarian cancer
This SuperSeries is composed of the following subset Series: GSE23553: Gene expression changes with induction of in-vitro platinum-resistance in ovarian cancer cell lines. GSE23554: Ovarian Cancer Dataset Refer to individual Series
ORGANISM(S): Homo sapiens 
2011-10-02 | E-GEOD-23603 | biostudies-arrayexpress
UnknownPersistent Imbalance: Women's Representation in North American Pediatric Cardiology Leadership Roles.
Not available
S-EPMC12418463 | biostudies-literature
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