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ProteomicsEpididymal epithelial degeneration and lipid metabolism impairment account for male infertility in occludin knockout mice
Occludin (OCLN) is a tight junction protein and Ocln deletion mutation causes male infertility in mice. However, the role of OCLN in male reproductive system remains unknown. In this study, we found defective proximal epididymis in Ocln-null mice with impaired sperm mobility and fertilization, but n...
ORGANISM(S): Mus Musculus 
2022-10-25 | PXD037690 |
ProteomicsProteome from whole epididymis and caput epididymidis of WT and Ocln knockout mice
Epithelial tight junction is the frontline barrier for physiological homeostasis and protection of a host and Occludin (Ocln) is a necessary component of the tight junction complex. Male Ocln knockout (Ocln-KO) mice are overall normal but infertile. The cause of this phenotype remains elusive. We fo...
ORGANISM(S): Mus Musculus 
2021-02-05 | PXD024008 |
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
ProteomicsA new long-acting tissue kallikrein ameliorates ischemic stroke injury by inhibiting HMGB1-related neuroinflammation and apoptosis
The proteomics analysis of total proteins extracted from the cerebral ischemic penumbra tissues of different groups three days after MCAO
ORGANISM(S): Mus Musculus 
PXD042777 |
ProteomicsA new long-acting tissue kallikrein ameliorates ischemic stroke injury by inhibiting HMGB1-related neuroinflammation and apoptosis-ip
Coimmunoprecipitation, detect binding protein of HMGB1 in primary microglials in control and LPS group
ORGANISM(S): Mus Musculus 
PXD042778 |
UnknownUltrahigh-energy gamma-ray emission associated with black hole-jet systems.
Not available
S-EPMC12746838 | biostudies-literature
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