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TranscriptomicsWidespread over-expression of the X chromosome in sterile F1 hybrid mice
We used a reciprocal cross of Mus musculus and M. domesticus in which F1 males are sterile in one direction and fertile in the other direction, in order to associate expression differences with sterility. Four different crosses were performed. A cross between two strains within each mouse species (M...
ORGANISM(S): Mus musculus musculus x M. m. domesticus 
2010-10-05 | E-GEOD-17684 | biostudies-arrayexpress
TranscriptomicsGene expression profile of liver tissue in carbon tetrachloride (CCl4)-treated mouse treated with erlotinib
Gene-expression profiles of liver tissue of cabon tetrachloride (CCl4)-treated mouse and the effect of erlotinib Hepatocellular carcinoma (HCC) is the sixth most common solid tumor worldwide and the third leading cause of cancer-related death. Given the lack of successful treatment options, chemopre...
ORGANISM(S): Mus musculus 
2014-02-28 | E-GEOD-27640 | biostudies-arrayexpress
TranscriptomicsTranscriptional reprogramming of tumor-associated endothelial cells by disruption of TNF-M-NM-1 signaling
Endothelial inflammation contributes to the pathogenesis of numerous human diseases; however, the role of tumor endothelial inflammation in the growth of experimental tumors and its influence on the prognosis of human cancers is less understood. TNF-M-NM-1, an important mediator of tumor stromal inf...
ORGANISM(S): Mus musculus 
2012-10-20 | E-GEOD-33253 | biostudies-arrayexpress
ProteomicsA novel mechanism for NF-kB activation via IkB aggregation
Proteins which interact with IkBa in insoluble aggregates known as Mallory-Denk bodies were characterized by AP-MS, Biotinylation by antibody recognition (BAR), and LCMS analysis of detergent solubalized aggregates. See the supplementary table (S12) for file annotation.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-08-31 | MSV000086042 | MassIVE
TranscriptomicsInterspecific Introgressive Origin of Genomic Diversity in the House Mouse
We report on a genome-wide scan for introgression in the house mouse (Mus musculus domesticus) involving the Algerian mouse (Mus spretus), using 20 samples from the ranges of sympatry and allopatry. Our analysis reveals significant variability in introgression signatures along the genomes, as well a...
ORGANISM(S): Mus musculus domesticus 
2014-11-01 | E-GEOD-62906 | biostudies-arrayexpress
GenomicsMeis IBA ChIP-seq
Chromatin immunoprecipitation using pan-Meis antibodies in first branchial arch cells from E11.5 mouse embryos detected by SOLiD sequencing
ORGANISM(S): Mus musculus 
2015-02-02 | E-MTAB-1631 | biostudies-arrayexpress
GenomicsMeis IIBA ChIP-seq
Chromatin immunoprecipitation using pan-Meis antibodies in second branchial arch cells from E11.5 mouse embryos detected by SOLiD sequencing
ORGANISM(S): Mus musculus 
2015-02-02 | E-MTAB-1632 | biostudies-arrayexpress
GenomicsPbx IIBA ChIP-seq
Chromatin immunoprecipitation using pan-Pbx antibodies in second branchial arch cells from E11.5 mouse embryos detected by SOLiD sequencing
ORGANISM(S): Mus musculus 
2015-02-02 | E-MTAB-1633 | biostudies-arrayexpress
GenomicsFoxc1 IIBA ChIP-seq
Chromatin immunoprecipitation using Foxc1 antibodies in second branchial arch (IIBA) cells from E11.5 mouse embryos detected by SOLiD sequencing
ORGANISM(S): Mus musculus 
2015-02-02 | E-MTAB-2696 | biostudies-arrayexpress
MetabolomicsThe Sphingolipidome of the model organism Caenorhabditis elegans
Sphingolipids are important lipids and integral members of membranes, where they form small microdomains called lipid rafts. These rafts are enriched in cholesterol and sphingolipids, which influences biophysical properties. Interestingly, the membranes of the biomedical model organism Caenorhabditi...
2024-04-01 | MTBLS963 | MetaboLights
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