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TranscriptomicsMouse bone marrow Mesenchymal Stem Cells (MSC) exposed to activated T cells
To analyze the changes induced in MSC transcriptome by activated T cells, MSC were co-cultured in transwell with anti CD3/CD28 activated T cells for 48 hrs before RNA extraction IFNγ-induced plasticity of mesenchymal stem cells is regulated by STATs through inhibition of mTOR and TGFβ pathways. Vi...
ORGANISM(S): Mus musculus 
2015-12-08 | E-GEOD-75749 | biostudies-arrayexpress
TranscriptomicsMouse bone marrow Mesenchymal Stem Cells (MSC) exposed to activated T cells
To analyze the changes induced in MSC transcriptome by activated T cells, MSC were co-cultured in transwell with anti CD3/CD28 activated T cells for 48 hrs before RNA extraction IFNγ-induced plasticity of mesenchymal stem cells is regulated by STATs through inhibition of mTOR and TGFβ pathways. Vigo...
ORGANISM(S): Mus musculus 
2015-12-08 | GSE75749 | GEO
UnknownRevealing the genetic basis of multiple sclerosis: are we there yet?
Not available
S-EPMC3105160 | biostudies-literature
Transcriptomicslongitudinal expression profiling in whole blood of multiple sclerosis patients and controls [MS vs Ctrl Discovery dataset]
Multiple sclerosis is the most common autoimmune disease of the central nervous system. Studying whole blood RNA from a cohort of 195 MS patients and 66 healthy controls, we identified gene expression signatures for interferon treatment and disease status by microarray analysis. Blood was collected ...
ORGANISM(S): Homo sapiens 
2013-06-17 | E-GEOD-41848 | biostudies-arrayexpress
Transcriptomicslongitudinal expression profiling in whole blood of multiple sclerosis patients and controls [IFN_discovery dataset]
Multiple sclerosis is the most common autoimmune disease of the central nervous system. Studying whole blood RNA from a cohort of 195 MS patients and 66 healthy controls, we identified gene expression signatures for interferon treatment and disease status by microarray analysis. Blood was collected ...
ORGANISM(S): Homo sapiens 
2013-06-17 | E-GEOD-41846 | biostudies-arrayexpress
Transcriptomicslongitudinal expression profiling in whole blood of multiple sclerosis patients and controls [IFN_replication dataset]
Multiple sclerosis is the most common autoimmune disease of the central nervous system. Studying whole blood RNA from a cohort of 195 MS patients and 66 healthy controls, we identified gene expression signatures for interferon treatment and disease status by microarray analysis. Blood was collected ...
ORGANISM(S): Homo sapiens 
2013-06-17 | E-GEOD-41847 | biostudies-arrayexpress
TranscriptomicsLongitudinal expression profiling in whole blood of multiple sclerosis patients and controls
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-06-17 | E-GEOD-41850 | biostudies-arrayexpress
UnknownIn depth comparison of an individual's DNA and its lymphoblastoid cell line using whole genome sequencing.
Not available
S-EPMC3473256 | biostudies-literature
TranscriptomicsInvestigation of somatic copy number variation in MZ twins
There is growing evidence that genomic DNA sequence changes occur in individual somatic cells during the lifetime of an individual and accumulation of these changes may influence aging and disease. In light of this, and contradicting reports regarding discordant copy number profiles between MZ twins...
ORGANISM(S): Homo sapiens 
2010-12-11 | E-GEOD-25826 | biostudies-arrayexpress
TranscriptomicsTranscriptional Activity in Lymph Nodes During the Initiation and Progression of Autoimmune Encephalomyelitis
NOD mice (8- to 13-wk-old) were bred and maintained at the La Trobe University Central Animal House (Bundoora, Melbourne, Australia). All experiments were conducted in accordance with the Australian code of practice for the care and use of animals for scientific purposes (National Health and Medical...
ORGANISM(S): Mus musculus 
2008-04-03 | E-GEOD-7461 | biostudies-arrayexpress
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