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TranscriptomicsGlobal transcriptome analysis of B. burgdorferi during adherence and invasion of human neuroglial cells
As adherence and entry of a pathogen into a host cell are two key components to an infection, identifying the molecular mechanisms responsible for cellular association will provide a better understanding of a microbe’s ability for pathogenesis. We previously established an in vitro model for B. b...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-8219 | biostudies-arrayexpress
UnknownMutation in the βA3/A1-crystallin gene impairs phagosome degradation in the retinal pigmented epithelium of the rat.
Not available
S-EPMC3031366 | biostudies-literature
UnknownProteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions.
Not available
S-EPMC2577212 | biostudies-literature
UnknownEffects of Inosine-5'-monophosphate Dehydrogenase (IMPDH/GuaB) Inhibitors on <i>Borrelia burgdorferi</i> Growth in Standard and Modified Culture Conditions.
Not available
S-EPMC11509813 | biostudies-literature
ProteomicsProtein Microarray Analysis of Antibody Responses of Experimentally Infected Dogs to Borrelia burgdorferi Antigens
Lyme borreliosis (LB) is a tick-borne infection caused by Borrelia burgdorferi. Dogs are at high risk of exposure to ticks and tick-borne pathogens, including B. burgdorferi. Immunodiagnostic assays are usually based on whole-cell preparations of B. burgdorferi as substrate and, consequently, interp...
ORGANISM(S): Canis lupus familiaris 
2013-08-22 | E-GEOD-50074 | biostudies-arrayexpress
UnknownDifferential telomere processing by Borrelia telomere resolvases in vitro but not in vivo.
Not available
S-EPMC1636258 | biostudies-literature
ProteomicsProtein Microarray Analysis of Antibody Responses of Experimentally Infected Dogs to Borrelia burgdorferi Antigens OspC
Lyme borreliosis (LB) is a tick-borne infection caused by Borrelia burgdorferi. Dogs are at high risk of exposure to ticks and tick-borne pathogens, including B. burgdorferi. Immunodiagnostic assays are usually based on whole-cell preparations of B. burgdorferi as substrate and, consequently, interp...
ORGANISM(S): Canis lupus familiaris 
2013-08-22 | E-GEOD-50075 | biostudies-arrayexpress
ProteomicsInferring Epitopes of a Polymorphic Antigen Amidst Broadly Cross-Reactive Antibodies Using Protein Microarrays: a Study of OspC Proteins of Borrelia burgdorferi
Epitope mapping studies aim to identify the binding sites of antibody-antigen interactions to enhance the development of vaccines, diagnostics and immunotherapeutic compounds. However, mapping is a laborious process employing time- and resource-consuming M-bM-^@M-^Xwet benchM-bM-^@M-^Y techniques o...
ORGANISM(S): Peromyscus leucopus 
2013-04-12 | E-GEOD-45996 | biostudies-arrayexpress
UnknownDifferences in the Platelet mRNA Landscape Portend Racial Disparities in Platelet Function and Suggest Novel Therapeutic Targets.
Not available
S-EPMC9724147 | biostudies-literature
UnknownIslet amyloid polypeptide is a target antigen for diabetogenic CD4+ T cells.
Not available
S-EPMC3161333 | biostudies-literature
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