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TranscriptomicsIdentification of the Candida albicans CAP1 regulon
Cap1p, a transcription factor of the basic region-leucine zipper family, controls the oxidative stress response in Candida albicans. It was shown that alteration of the C-terminal cysteine-rich domain (CRD) of Cap1p results in nuclear retention and constitutive transcriptional activation. To further...
ORGANISM(S): Candida albicans 
2010-05-18 | E-GEOD-14258 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression profile analysis of the Candida glabrata Pdr1 regulon
The ABC-transporters CgCdr1, CgPdh1, and CgSnq2 are known to mediate azole resistance in the pathogenic fungus Candida glabrata. Activating mutations in CgPDR1, a zinc cluster transcription factor, result in constitutive up-regulation of these ABC-transporter genes but to varying degrees. We examine...
ORGANISM(S): Candida glabrata 
2011-02-21 | E-GEOD-24168 | biostudies-arrayexpress
TranscriptomicsIdentification of the Candida albicans Cap1p regulon (Cap1-CSE-HA and Cap1-HA complete datasets)
Cap1p, a transcription factor of the basic region-leucine zipper family, regulates oxidative stress response (OSR) in Candida albicans. Alteration of its C-terminal cysteine-rich domain (CRD) results in Cap1p nuclear retention and transcriptional activation. To better understand the function of Ca...
ORGANISM(S): Candida albicans 
2010-05-18 | E-GEOD-15104 | biostudies-arrayexpress
TranscriptomicsMitochondrial two-component signaling systems in Candida albicans
Two-component signal transduction pathways are one of the primary means by which microorganisms respond to environmental signals. These signaling cascades originated in prokaryotes and were inherited by eukaryotes via endosymbiotic lateral gene transfer from ancestral cyanobacteria. We report here t...
ORGANISM(S): Candida albicans 
2013-07-02 | E-GEOD-45438 | biostudies-arrayexpress
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