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TranscriptomicsA Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes
A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function Understanding the cell-cell interactions that control CNS development and function has long been limited by the lack of methods to cleanly separate astrocytes, neu...
ORGANISM(S): Mus musculus 
2007-12-30 | E-GEOD-9566 | biostudies-arrayexpress
TranscriptomicsIdentification of Myelin-gene Regulatory Factor as a Critical Transcriptional Regulator Required for CNS Myelination
The transcriptional control of CNS myelin gene expression is poorly understood. Here we identify gene model 98, which we have named Myelin-gene Regulatory Factor (MRF), as a transcriptional regulator required for CNS myelination. Within the CNS, MRF is specifically expressed by postmitotic oligodend...
ORGANISM(S): Mus musculus 
2009-05-31 | E-GEOD-15303 | biostudies-arrayexpress
TranscriptomicsA survey of human brain transcriptome diversity at the single cell level
We used single cell RNA sequencing on 466 cells to capture the cellular complexity of the adult and fetal human brain at a whole transcriptome level. Healthy adult temporal lobe tissue was obtained from epileptic patients during temporal lobectomy for medically refractory seizures. We were able to c...
ORGANISM(S): Homo sapiens 
2015-05-20 | E-GEOD-67835 | biostudies-arrayexpress
TranscriptomicsAn RNA-Seq transcriptome and splicing database of neurons, glia, and vascular cells of the cerebral cortex
Purpose: To better understand the function of the various cell types of the brain, we prospectively purified neurons, astrocytes, oligodendrocyte precursor cells, newly formed oligodendrocytes, myelinating oligodendrocytes, microglia, endothelial cells, and pericytes from mouse cerebral cortex. We g...
ORGANISM(S): Mus musculus 
2014-08-15 | E-GEOD-52564 | biostudies-arrayexpress
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