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TranscriptomicsCharacterization of a P-REX1 gene signature in breast cancer cells
The Rac nucleotide Exchange Factor (Rac-GEF) P-Rex1 is highly expressed in breast cancer, specifically in the luminal subtype, and is an essential mediator of actin cytoskeleton reorganization and cell migratory responses induced by ErbB and other tyrosine-kinase receptors. Heregulin, a growth facto...
ORGANISM(S): Homo sapiens 
2016-09-07 | E-GEOD-77974 | biostudies-arrayexpress
TranscriptomicsA new Agilent 15K cross strain P. falciparum microarray optimized for the transcriptome analysis of Indian P. falciparum isolates
Genomic variation is an inherent phenomena observed among members of same species belonging to different geographical locations. In case of P. falciparum, an apicomplexan protozoan parasite, its 22.8 MB nuclear genome is known to display vast genetic diversity in the subtelomeric compartments havin...
ORGANISM(S): Plasmodium falciparum 
2016-01-17 | E-GEOD-54253 | biostudies-arrayexpress
TranscriptomicsP. falciparum Complicated Malaria: Modulation and Connectivity between Exportome and Variant Surface Gene Families
In temperate and sub-tropical regions of Latin America, complicated malaria manifested as hepatic dysfunction or renal dysfunction is seen in all age groups. There has been a concerted focus on understanding the patho-physiological and molecular basis of complicated malaria in children, much less is...
ORGANISM(S): Plasmodium falciparum 
2015-07-07 | E-GEOD-59844 | biostudies-arrayexpress
TranscriptomicsParedes_IPATIMUP_Comparison of cell lines derived from BT-20 cells using siRNA to silence E-cadherin and P-cadherin
Gene expression of four cell lines derived from BT-20 cells, namely, BT20 siCtr (E+/P+), BT20 siPcad (E+/P-), BT20 siEcad (E-/P+), and BT20 siEPcad (E-/P-) was compared using Agilent Human GE 4x44k v2 Microarrays and the Agilent One-Color Microarray-Based Gene Expression Analysis protocol (Quick Amp...
ORGANISM(S): Homo sapiens 
2011-10-01 | E-MEXP-3329 | biostudies-arrayexpress
TranscriptomicsNatural anitsense transcripts in Plasmodium vivax clinical isolates
Plasmodium vivax is the most geographically widespread human malaria parasite causing approximately 130-435 million infections annually. It is an economic burden in many parts of the world and poses a public health challenge along with the other Plasmodium sp. The biology of this parasite is very li...
ORGANISM(S): Plasmodium vivax 
2014-01-16 | E-GEOD-45165 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of purified P-bodies from HEK293 cells
To identify RNAs accumulating in P-bodies (cytoslic RNP granules), P-bodies were purified from HEK293 cell extracts using a Flow Activated Particle Sorting (FAPS) method. Sorted P-bodies were compared to the pre-sorted fraction to identify RNA enriched in P-bodies.
ORGANISM(S): Homo sapiens 
2017-09-01 | E-MTAB-5477 | biostudies-arrayexpress
TranscriptomicsEffect of germline ablation in the nematode P. pacificus
Transcriptional profiling of germline-ablated P. pacificus worms versus un-ablated wild-type controls. Food source E. coli OP50 for both conditions. The goal was to identify genes that regulate the enhanced longevity observed in germline-deficient animals. One-condition experiments. Germline ablated...
ORGANISM(S): Pristionchus pacificus 
2012-04-17 | E-GEOD-37331 | biostudies-arrayexpress
ProteomicsDetermination of specificity of the MAbs to Der p 21
For determination of specificity of the MAbs, rDer p 21, thermally denatured rDer p 21 and rMBP-Der p 21 (0.3 mg/mL) were printed. the slides were incubated for 2 h 5 different MAbs (0.5 µg/mL for specificity analysis). Then the slides were incubated for 30 min goat anti-mouse IgG Fc Alexa Fluor® 6...
ORGANISM(S): Mus musculus 
2023-12-25 | E-MTAB-13625 | biostudies-arrayexpress
Proteomicsdetermination of 5 different Mab reactivity to rDer p 21 and nDer p 21 in HDM extracts
For determination of reactivity with rDer p 21 and Der p 21 in extracts, a serially diluted rDer p 21 from 100 to 0.00305 µg/mL and 6 different HDM extracts diluted 16 times from their stock concentrations were printed. Human serum albumin, rMBP, HRP and PBS were printed as negative controls. Each a...
ORGANISM(S): Mus musculus 
2023-12-24 | E-MTAB-13590 | biostudies-arrayexpress
TranscriptomicsImmune reposne of germline-ablated P. pacificus exposed to S. marcescens
Transcriptional profiling of germline-ablated P. pacificus worms exposed to S. marcescens for 8 hours versus germline-ablated P. pacificus exposed to the control E. coli OP50. First goal was to identify genes that are involved in immune response of germline-ablated P. pacificus when exposed to S. ma...
ORGANISM(S): Pristionchus pacificus 
2012-04-17 | E-GEOD-37337 | biostudies-arrayexpress
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