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TranscriptomicsExpression profiles of primary bone marrow derived mouse macrophages M-bM-^@M-^S untreated and treated with LPS or LPS+PGE
The polarization of macrophages into an anti-inflammatory or regulatory phenotype plays an important role in resolving inflammation. PGE2 regulates macrophage polarization via a PKA dependent pathway. PKA phosphorylates SIKs, inhibiting their ability to phosphorylate CRTC3 in cells. This in turn ...
ORGANISM(S): Mus musculus 
2013-02-06 | E-GEOD-41833 | biostudies-arrayexpress
Genomicsheat shock SUMO-2 ChIP-seq
Analysis of changes in SUMO-2 binding to chromatin in response to heat shock in human U2OS cells
ORGANISM(S): Homo sapiens 
2015-07-13 | E-MTAB-2368 | biostudies-arrayexpress
UnknownEvolutionary temperature compensation of carbon fixation in marine phytoplankton.
Not available
S-EPMC7078849 | biostudies-literature
GenomicsA role for Snf2 related nucleosome spacing enzymes in genome-wide nucleosome organization
The positioning of nucleosomes within the coding regions of eukaryotic genes is aligned with respect to transcriptional start sites. This organization is likely to influence many genetic processes, requiring access to the underlying DNA. Here we show that the combined action of Isw1 and Chd1 nucleos...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-16 | E-GEOD-31015 | biostudies-arrayexpress
TranscriptomicsTranscription profiling during differentiation of the neural tube in HH stage 10 chick embryos
The spinal cord is generated progressively as cells leave the caudal region of the elongating body axis such that the temporal steps of neural differentiation become spatially separated along the head to tail axis. At key stages, it is therefore possible to isolate near-adjacent cell populations fro...
ORGANISM(S): Gallus gallus 
2014-08-01 | E-MTAB-2734 | biostudies-arrayexpress
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