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Early development in humans is characterised by low and variable embryonic viability, reflected in low fecundity and high rates of miscarriage, relative to other mammals. Data from assisted reproduction programmes provides additional evidence that this is largely mediated at the level of embryonic ...
ORGANISM(S): Homo sapiens 
Paired end Illumina sequencing of whole exomes of multiple tumour regions.
We applied multi-region exome sequencing to 10 clear cell renal carcinomas to resolve the genetic architecture, intra tumour heterogeneity and evolutionary histories of these tumours.
Data Access Committee EGAC00001001907
Van Hippel-Lindau syndrome multi-region exome sequencing of two patients
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