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TranscriptomicsGene expression profiles of livers from mice fed high-fat diet and high fructose-glucose solution for 8 weeks
The lack of a preclinical model of nonalcoholic steatohepatitis (NASH) and hepatocellular cancer (HCC) that recapitulates human disease is a major barrier to therapeutic development. We report a high fat-high sugar diet-induced NASH and HCC in a stable isogenic 129S1/SvImJ crossed with C57Bl/6J mice...
ORGANISM(S): Mus musculus 
2016-07-25 | E-GEOD-67678 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of livers and liver tumors from mice fed high-fat diet and high fructose-glucose solution for 52 weeks
The lack of a preclinical model of nonalcoholic steatohepatitis (NASH) and hepatocellular cancer (HCC) that recapitulates human disease is a major barrier to therapeutic development. We report a high fat-high sugar diet-induced NASH and HCC in a stable isogenic 129S1/SvImJ crossed with C57Bl/6J mice...
ORGANISM(S): Mus musculus 
2016-07-25 | E-GEOD-67679 | biostudies-arrayexpress
TranscriptomicsA preclinical mouse model of nonalcoholic steatohepatitis and hepatocellular cancer that mimics human disease
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-07-25 | E-GEOD-67680 | biostudies-arrayexpress
UnknownCharacterization and expression of the cytochrome P450 gene family in diamondback moth, Plutella xylostella (L.).
Not available
S-EPMC5155450 | biostudies-literature
UnknownMAPK signaling pathway alters expression of midgut ALP and ABCC genes and causes resistance to Bacillus thuringiensis Cry1Ac toxin in diamondback moth.
Not available
S-EPMC4395465 | biostudies-literature
TranscriptomicsTranscription profiling of human dendritic cells matured by cadherin reveals disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation
The maturation of dendritic cells (DCs) after exposure to microbial products or inflammatory mediators plays a critical role in initiating the immune response. We found that maturation can also occur under steady state conditions, triggered by alterations in E-cadherin-mediated DC-DC adhesion. Sele...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9241 | biostudies-arrayexpress
UnknownQuality of life drives patients' preferences for secondary findings from genomic sequencing.
Not available
S-EPMC7609335 | biostudies-literature
UnknownHigh resolution diffusion imaging in the unfixed post-mortem infant brain at 7T.
Not available
S-EPMC12043270 | biostudies-literature
Unknown"I don't need any more unknowns hanging over my head": Views of patients with cancer on variants of uncertain significance and low/moderate risk results from genomic sequencing.
Not available
S-EPMC11262616 | biostudies-literature
UnknownVariation among 532 genomes unveils the origin and evolutionary history of a global insect herbivore.
Not available
S-EPMC7211002 | biostudies-literature
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