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GenomicsChIP-Seq experiment to analyse Zip1 localisation in the Ctf19c mutants during meiotic prophase.
The goal of this experiment is to confirm whether Ctf19c mutants affect Zip1 localisation during meiotic prophase. To do so, diploid S. cerevisiae SK1 cells were constructed containing ndt80-d to arrest cells in prophase. Cells were allowed to sporulate in sporulation media for 5 hours after which f...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-15 | E-GEOD-70029 | biostudies-arrayexpress
GenomicsRec8 ChIP-Seq experiment to analyse cohesin localisation in the Ctf19c mutants during meiotic prophase.
Ctf19c mutants were shown to specifically impair cohesin localisation at the pericentromere during mitosis. The goal of this experiment is to confirm whether this mutant has the same effect on cohesin localisation during meiotic prophase. To do so, diploid S. cerevisiae SK1 cells were constructed co...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-15 | E-GEOD-70030 | biostudies-arrayexpress
GenomicsShugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere
To protect against aneuploidy, chromosomes must attach to microtubules from opposite poles (“biorientation”) prior to their segregation during mitosis. Biorientation relies on the correction of erroneous attachments by the aurora B kinase, which destabilizes kinetochore-microtubule attachments that ...
ORGANISM(S): Saccharomyces cerevisiae W303 
2014-01-08 | E-GEOD-53856 | biostudies-arrayexpress
GenomicsCondensin association with chromosomes depends on a DNA binding domain formed by its HEAT-repeat subunits
Condensin protein complexes play central roles in the three-dimensional organization of chromosomes during mitotic and meiotic cell divisions. How condensin interacts with its chromatin substrates to promote sister chromatid decatenation and segregation is largely unknown. Previous work suggested th...
ORGANISM(S): Saccharomyces cerevisiae 
2014-05-16 | E-GEOD-55948 | biostudies-arrayexpress
Genomicslocalization of Scc2 between wild type and scc4-m35 cells in S-phase
Wild-type (AM15307) and scc4-m35 (AM15311) cells carrying SCC2-3FLAG were fixed for 2 hr, 15 min following an a-factor arrest. Samples were harvested, anti-HA ChIP was performed and both input and IP samples were sequenced for both strains. ChIP-seq for S. cerevisiae Scc2-3FLAG in S-phase cells in W...
ORGANISM(S): Saccharomyces cerevisiae 
2016-07-21 | E-GEOD-70316 | biostudies-arrayexpress
GenomicsChIP-Seq experiments to analyse Rec8 and Zip1 localisation in Ctf19c mutants during meiotic prophase
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-15 | E-GEOD-70032 | biostudies-arrayexpress
GenomicsStructural evidence for Scc4-dependent localization of cohesin loading
Purpose: The Goal of this study is to look at 1) Differences in genome wide localization of Scc2 between wild type and scc4-m35 cells in S-phase 2) Differences in genome wide localisation of Scc1 cohesin between wild type and scc4-m35 in metaphase arrested cells. Method: 1) Wild-type (AM15307) and...
ORGANISM(S): Saccharomyces cerevisiae 
2015-06-05 | E-GEOD-68573 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA sequencing of VE-Cadherin+ cells isolated from mouse E10.5 aorta-gonad-mesonephros region.
The aim of this experiment was to investigate cellular heterogeneity of VE-Cadherin+ cells isolated from mouse E10.5 aorta-gonad-mesonephros region.
ORGANISM(S): Mus musculus 
2019-03-12 | E-MTAB-6987 | biostudies-arrayexpress
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