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Spatial Transcriptomics of Liver tissue with Bcatenin exon3 genetic mutations.
Gene expression was profiled in different regions of mouse liver with either Bcatenin exon3 mutation or Bcatenin exon3/Myc mutation at the noted time points.
ORGANISM(S): synthetic construct Mus musculus 
2023-04-28 | GSE230644 | GEO
Transcriptional profiling of Liver tissue from mice with bcatenin and Myc mutations
The effect of combinations Apc, Bcatenin and Myc mutation on mouse liver was examined with RNAseq at two time points.
ORGANISM(S): Mus musculus 
2023-04-28 | GSE230137 | GEO
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide. β-catenin is widely thought to be a major oncogene in HCC based on the frequency of mutations associated with aberrant Wnt signaling in HCC patients. Challenging this model, our data reveal that β-catenin ...
ORGANISM(S): Mus musculus (Mouse) 
2019-03-29 | PXD013095 | Pride
We report that miR3607 controls the embryonic cerebral cortex development by regulating neurogenesis, neuron migration and axon growth in a bCatenin signaling pathway dependent manner.
ORGANISM(S): Mus musculus 
2022-01-12 | GSE135321 | GEO
During mammalian gastrulation, pluripotent epiblast stem cells migrate through the primitive streak to form the multipotent progenitors of the mesoderm and endoderm germ layers. Msgn1 is a bHLH transcription factor and is a direct target gene of the Wnt/bcatenin signaling pathway. Msgn1 is expressed...
ORGANISM(S): Mus musculus 
2011-07-01 | GSE29848 | GEO
During mammalian gastrulation, pluripotent epiblast stem cells migrate through the primitive streak to form the multipotent progenitors of the mesoderm and endoderm germ layers. Msgn1 is a bHLH transcription factor and is a direct target gene of the Wnt/bcatenin signaling pathway. Msgn1 is expressed...
ORGANISM(S): Mus musculus 
Bmps and Wnts play opposing roles in several contexts during chondrogenesis and joint formation. Using genetic and genomic approaches, we found instead that canonical Wnts can cooperate with Bmps to enhance pSmad1/5 activity and initiate chondrogenic commitment in digit tip progenitors. 5’HoxdD/D mu...
ORGANISM(S): Mus musculus 
2026-04-24 | GSE317957 | GEO
The objective of this study was to identify the direct target genes of M-NM-2-catenin acting downstream of canonical Wnt signaling in mouse embryonic stem cells (ESCs).Canonical Wnt signaling supports the pluripotency of mouse ESCs but also promotes differentiation of early mammalian cell lineages. ...
ORGANISM(S): Mus musculus 
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