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Alzheimers disease and epilepsy are reciprocally related. Among sporadic AD patients, seizures occur in 10-22 percent, and subclinical epileptiform abnormalities occur in 22-5 percent. Cognitive deficits, with prominent short-term memory impairments, occur in most epilepsy patients. Common neurophys...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-02-27 | MSV000091370 | MassIVE
Using unbiased localized proteomics, we analyzed amyloid plaques and adjacent plaque-devoid tissue (non-plaque) from post-mortem paraffin-embedded tissues in three cohorts (n=20/group): Down Syndrome, Early Onset AD, and Late Onset AD. We assessed functional associations using Gene Ontology (GO) enr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-05-18 | MSV000094800 | MassIVE
This study compares the transcriptomes of wild (Figgjo) and domesticated (Mowi) Atlantic salmon embryos, employing a custom 44k oligonucleotide microarray to identify gene pathways perturbed between wild and domesticated strains and with the aid of heir reciprocal hybrids, to examine the heritabilit...
ORGANISM(S): Salmo salar 
This study compares the transcriptomes of wild and domesticated Atlantic salmon strains and their transcriptional response to acute stress. Microarray interrogations consisted of 48 hybridizations; 4 crosses (pure wild; Figgjo x Figgjo, pure domesticated; Mowi x Mowi and their reciprocal hybrids; Fi...
ORGANISM(S): Salmo salar 
Atlantic salmon (Salmo salar) has been selectively bred in Europe since the 1970s and the process of domestication has led to both phenotypic and genotypic differences between wild and farmed fish. Despite strict regulations large numbers of fish escape annually from fish farms, a concern for both a...
ORGANISM(S): Salmo salar 
Sepsis is an extreme inflammatory response to infection that occurs in the bloodstream and causes damage throughout the body. Glycosylation is known to play a role in immunity and inflammation, but the role of glycans in sepsis is not well defined. Herein, we profiled the serum glycomes of experimen...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-12-05 | MSV000088518 | MassIVE
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