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ProteomicsIloprost (2/5 nM) stimulated Platelets
TiO2 enriched phosphopeptides of Iloprost stimulated platelets were digested with trypsin and labeled with iTRAQ. Samples were analysed by nano LC-MS/MS on an LTQ OrbitrapVelos (Thermo Scientific) coupled to an Ultimate 3000 Liquid Chromatography system (Dionex). Peptides were concentrated on a self...
ORGANISM(S): Homo sapiens (Human) 
2013-12-02 | PXD000242 | Pride
Phosphopeptides Itraq Iloprost Platelets 
ProteomicsQuantitative Phosphorylation analysis in human platelets after ADP stimulation
Human platelets were treated with 20 µM of ADP for 10, 30 and 60 s in triplicate. In a second experiment blood donations of three donors were split again in four fractions and one was treated with 20 µM of ADP and the second and third with 20 µM of ADP for 30 s and subsequently with 2 nM of Ilopros...
ORGANISM(S): Homo sapiens (Human) 
2017-03-14 | PXD001189 | Pride
Phosphorylation Platelets Adp stimulation 
MetabolomicsRare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism

We investigated the cumulative contribution of rare, exonic genetic variants on the concentration of 1,487 metabolites and 53,714 metabolite ratios in urine by performing gene-based tests based on 226,233 variants from up to 4,864 participants of the German Chronic Kidney Disease (GCKD)...

2021-03-09 | MTBLS284 | MetaboLights
ProteomicsOptimized parameter settings enhance proteome-wide formation of crosslinks on low-abundant proteins
Studies using crosslinking coupled to mass spectrometry on the proteome-wide level have spurred great interest as they facilitate structural probing of protein interactions in living cells or even organisms. Here we show, by using both an in-vitro mimic of a crowded cellular environment and eukaryot...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-02-17 | PXD014759 | Pride
Proteome-wide xl-ms Reaction kinetics 
UnknownDrosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.
Not available
S-EPMC4426361 | biostudies-literature
ProteomicsThe impact II, a very high resolution quadrupole time-of-flight instrument for deep shotgun proteomics
Hybrid quadrupole time-of-flight (QTOF) is one of the two major mass spectrometric technologies used in proteomics. Although based on simple fundamental principles, it has over the last decades greatly evolved in terms of achievable resolution, mass accuracy and dynamic range. The Bruker impact plat...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Saccharomyces Cerevisiae (ncbitaxon:4932) Mus Musculus (ncbitaxon:10090) 
2016-07-19 | MSV000079935 | MassIVE
ProteomicsM.musculus - Cerebellum, iBAQ (Becketal.,molcellproteomics2015)
abundance based on iBAQ, Interaction consistency score: 19.7, Coverage: 48
ORGANISM(S): 10090 
2015-00-00 | 1779616615 | PAXDB
MetabolomicsSystematic analyses of lipid mobilization by human lipid transfer proteins

Lipid transfer proteins (LTPs) maintain the specialised lipid compositions of biological membranes, and many are associated with disease. In eukaryotes, they support organellar functions by transporting lipids between compartmentalised metabolic pathways. However, for the majority of the hundreds...

2025-11-14 | MTBLS9567 | MetaboLights
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
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