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ProteomicsProteolytic processing of CD99
The adhesion molecule CD99 is essential for transendothelial migration (TEM) of leukocytes. Here we demonstrate by biochemical and cellular assays that CD99 undergoes ectodomain shedding by the metalloprotease meprin ? and subsequent intramembrane proteolysis by ?-secretase. The cleavage site in CD9...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080746 | MassIVE
TranscriptomicsRNA-seq of Arabidopsis thaliana leaves for three genotypes (Col-0 wild type, gsnor1-3, axe1-5/hda6) in low light and dark conditions
Plants were grown for 4 weeks under short day (10 h light/14 h dark and 20 °C/16 °C, respectively). The relative humidity during the day and night was 50 %. Then, plants were transferred at 11 am (5 h after turning on the light) for 4 h either to dark (D, 0 µE, 22 °C) or low light (LL, 100-130 µE, ...
ORGANISM(S): Arabidopsis thaliana 
2021-05-28 | E-MTAB-9301 | biostudies-arrayexpress
TranscriptomicsHistone acetylation H3K9ac ChIP-seq of Arabidopsis thaliana leaves for three genotypes (Col-0 wild type, gsnor1-3, axe1-5/hda6) in low light and dark conditions
Plants were grown for 4 weeks under short day (10 h light/14 h dark and 20 °C/16 °C, respectively). The relative humidity during the day and night was 50 %. Then, plants were transferred at 11 am (5 h after turning on the light) for 4 h either to dark (0 µE, 22 °C) or low light (100-130 µE, 22 °C) c...
ORGANISM(S): Arabidopsis thaliana 
2021-05-28 | E-MTAB-9299 | biostudies-arrayexpress
TranscriptomicsThe activation potential of MOF is constrained for dosage compensation
The H4K16 acetyltransferase MOF plays a crucial role in dosage compensation in Drosophila, but has additional, global functions. We compared the molecular context and effect of MOF in male and female flies combining chromosome-wide mapping and transcriptome studies with analyses of defined reporter ...
ORGANISM(S): Drosophila melanogaster 
2010-06-26 | E-GEOD-20695 | biostudies-arrayexpress
UnknownSynthesis of a <sup>13</sup>C/<sup>2</sup>H Labeled Building Block to Probe the Phosphotyrosine Interactome Using Biomolecular NMR Spectroscopy.
Not available
S-EPMC11727006 | biostudies-literature
TranscriptomicsTranscription profiling of Medicago roots from MtTi2i vs control after infection with Aphanomyces euteiches
Comparsion of root transcriptome profiles after Aphanomyces euteiches infections between control and MtTi2i-lines
ORGANISM(S): Medicago truncatula 
2006-03-03 | E-MEXP-572 | biostudies-arrayexpress
UnknownNovel CH1:CL interfaces that enhance correct light chain pairing in heterodimeric bispecific antibodies.
Not available
S-EPMC5914326 | biostudies-literature
TranscriptomicsThe MOF-containing NSL complex associates globally with housekeeping genes, but activates only a defined subset (RNAi)
The MOF-containing NSL complex binds to many but not all promoters of active genes and potentially contributes to their proper gene expression. It is currently unknown what determines whether an active gene is bound or not. Here, we provide evidence that the NSL complex primarily targets active prom...
ORGANISM(S): Drosophila melanogaster 
2011-10-28 | E-GEOD-30990 | biostudies-arrayexpress
TranscriptomicsThe MOF-containing NSL complex associates globally with housekeeping genes, but activates only a defined subset
This SuperSeries is composed of the following subset Series: GSE30989: MOF-containing NSL complex specifically binds promoters of most, but stimulates only a specific subset of, housekeeping genes (ChIP-chip dataset) GSE30990: MOF-containing NSL complex specifically binds promoters of most, but stim...
ORGANISM(S): Drosophila melanogaster 
2011-10-28 | E-GEOD-30991 | biostudies-arrayexpress
TranscriptomicsThe MOF-containing NSL complex associates globally with housekeeping genes, but activates only a defined subset (ChIP)
The MOF-containing NSL complex binds to many but not all promoters of active genes and potentially contributes to their proper gene expression. It is currently unknown what determines whether an active gene is bound or not. Here, we provide evidence that the NSL complex primarily targets active prom...
ORGANISM(S): Drosophila melanogaster 
2011-10-28 | E-GEOD-30989 | biostudies-arrayexpress
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