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Accumulation of excess nutrients hampers proper liver function and is linked to non-alcoholic fatty liver disease (NAFLD) in obesity. However, the signals responsible for an impaired adaptation of hepatocytes to obesogenic dietary cues remain still largely unknown. Post-translational modification b...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD041329 | Pride
Summary: Genetic disorders of muscle cause muscular dystrophy, and are some of the most common inborn errors of metabolism. Muscle also rapidly remodels in response to training and innervation. Muscle weakness and wasting is important in such conditions as aging, critical care medicine, space flig...
ORGANISM(S): Homo sapiens 
The data set consists of 32 S. aureus cytosolic samples that were collected by GFP supported cell sorting during infection in lung epithelial cells. The data include 8 time points (2.5 h, 6.5 h , 24 h, 48 h, 72 h, and 96 h post infection plus exponential and non-adherent control) that were collected...
ORGANISM(S): Staphylococcus Aureus Hg001 
Summary: Genetic disorders of muscle cause muscular dystrophy, and are some of the most common inborn errors of metabolism. Muscle also rapidly remodels in response to training and innervation. Muscle weakness and wasting is important in such conditions as aging, critical care medicine, space flight...
ORGANISM(S): Homo sapiens 
2005-10-14 | GSE3307 | GEO
Samples for mass spectrometry were prepared as follows. HEK293 cells (150 cm^2 dish) were transfected with 6 μg of each protein-coding plasmid by using TransIT (Mirus). Cell lysis and elution were performed as described above. For loading the samples onto an SDS-PAGE, glycerol was added to the elute...
ORGANISM(S): Homo Sapiens (human) 
Treatment of Mycobacterium tuberculosis infections is a challenging task due to a growing number of resistant clinical isolates as well as an almost empty drug development pipeline. To identify new antibiotic hits, we screened a focused library of 400 synthetic compounds derived from a recently disc...
ORGANISM(S): Mycobacterium tuberculosis H37Ra 
2025-05-06 | PXD050993 | Pride
The data set consists of 32 cytosolic samples of human bronchial epithelial cells that were collected during infection with S. aureus. The data include 8 (0h, 1h, 2.5 h, 6.5 h, 24 h, 48 h, 72 h, and 96 h post infection) time points that were collected out of four biological replicates. DIA data and ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
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