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MetabolomicsAge-independent Cardiac Protection by Pharmacological Activation of Beclin-1 During Endotoxemia and Its Association with Energy Metabolic Reprograming in Myocardium — A Targeted Metabolomics Study
Not available
ORGANISM(S): Mus musculus 
ST002178 | MetabolomicsWorkbench
ProteomicsADSL promotes autophagy and liver tumor growth through fumarate-mediated Beclin1 dimethylation
Huh7 cells with expression of Flag-Beclin1 were treated with lipid depletion. An immunoprecipitation assay was performed, and immunoprecipitates were subjected to masspec analysis.
ORGANISM(S): Homo sapiens (Human) 
2024-12-24 | PXD057286 | Pride
Beclin1 Liver tumor Adsl Autophagy 
GenomicsTranscriptiomics profiling of brown adipose tissue of adipocyte-specific Beclin1 knockout mice
Transcriptiomics profiling of brown adipose tissue of adipocyte-specific Beclin1 knockout mice
PRJNA623637 | ENA
GenomicsBeclin1 Deficiency Unlocks Cardiac Lineage Commitment through Convergent Wnt and BMP Signaling Activation
Beclin1 Deficiency Unlocks Cardiac Lineage Commitment through Convergent Wnt and BMP Signaling Activation
PRJNA1246102 | ENA
TranscriptomicsBeclin1 Deficiency Unlocks Cardiac Lineage Commitment through Convergent Wnt and BMP Signaling Activation
Beclin1 plays significant roles in cardiac organogenesis. Beclin1 can regulate the fate conversion of fibroblasts into cardiomyocytes. However, the function and mechanism of Beclin1 in regulating early cardiac lineage commitment and differentiation remain unclear. To explore its potential role in ca...
ORGANISM(S): Mus musculus 
2025-12-04 | GSE293719 | GEO
TranscriptomicsTranscriptiomics profiling of brown adipose tissue of adipocyte-specific Beclin1 knockout mice
Adipose mRNA profiles of wildetype and Beclin1 knockout (tamoxifen-induced Adipoq-CreER/Beclin1(floxed/floxed)) mice were generated by deep sequencing.
ORGANISM(S): Mus musculus 
2020-05-26 | GSE148275 | GEO
UnknownBeclin1 Deficiency Suppresses Epileptic Seizures.
Not available
S-EPMC9354790 | biostudies-literature
UnknownBECLIN1: Protein Structure, Function and Regulation.
Not available
S-EPMC8235419 | biostudies-literature
UnknownBcl-xL and UVRAG cause a monomer-dimer switch in Beclin1.
Not available
S-EPMC3258859 | biostudies-literature
Genomics
Strategy of Hepatic Metabolic Defects Induced by beclin1 Heterozygosity in Adult Zebrafish
PRJNA615045 | ENA
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