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TranscriptomicsRole of histone modifications in pervasive transcription and antisense-mediated silencing in yeast
Whole transcriptome analyses of various histone modification mutants in a Drrp6 strain using high-density tiling arrays. To assess the importance of histone modifications in antisense-mediated repression genome-wide, we performed high-density tiling arrays on cells lacking Rrp6 alone or combined wit...
ORGANISM(S): Saccharomyces cerevisiae 
2013-03-01 | E-MTAB-1316 | biostudies-arrayexpress
TranscriptomicsCell cycle- and chaperone-mediated regulation of H3K56ac incorporation in yeast
Acetylation of histone H3 lysine 56 is a covalent modification best-known as a mark of newly-replicated chromatin, but has also been linked to replication-independent histone replacement. Here, we measured H3K56ac levels at single-nucleosome resolution in asynchronously growing yeast cultures, as w...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-03 | E-GEOD-12822 | biostudies-arrayexpress
ProteomicsFunctionality of plant mechanoproteins is based on dual role of cysteines
Forisomes are giant polyprotein complexes that undergo an immense and fully reversible conformational change from a spindle into a plug-like state triggered by Ca2+ and pH changes. Resembling their native function in plant vasculature, forisomes can act as valves to efficiently regulate flow in micr...
ORGANISM(S): Medicago Truncatula 
2021-11-08 | PXD027153 | JPOST Repository
TranscriptomicsTranscription profiling by tiling array of yeast ssu72, rrp6, and rco1 mutants
Genome-wide analysis of ssu72 and rrp6 mutants in Yeast
ORGANISM(S): Saccharomyces cerevisiae 
2011-05-03 | E-TABM-936 | biostudies-arrayexpress
TranscriptomicsTrivalent arsenic inhibits the functions of chaperonin complex
The goal of this study was to identify yeast mutants with arsenite hypersensitivity. Keywords: dose response Matched pools of yeast knockout (YKO) mutants were grown in paired growth media lacking or containing arsenite at various concentrations. The relative abundances of the YKO mutants were profi...
ORGANISM(S): Saccharomyces cerevisiae 
2010-07-26 | E-GEOD-5973 | biostudies-arrayexpress
TranscriptomicsCotranslational signal independent SRP preloading during membrane targeting
Cotranslational targeting into the endoplasmic reticulum (ER) by the Signal Recognition Particle (SRP) is a key event determining polypeptide fate in eukaryotic cells. Here, we globally define the principles and mechanisms of SRP binding and ER targeting in vivo. Cotranslational targeting through SR...
ORGANISM(S): Saccharomyces cerevisiae 
2016-08-03 | E-GEOD-74393 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse dystrophin-deficient and dystrophin and utrophin double-deficient animalse crossed with mice with full-length hDMD genes
Crossing of hDMD mice that contain the full-length 2.3 Mb hDMD gene were crossed with dystrophin-deficient mdx mice and dystrophin and utrophin double-deficient mdx x utrn-/- mice resulted in a full rescue of the dystrophic features of these mice, as concluded from histological analysis. Analysis on...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6790 | biostudies-arrayexpress
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